Literature DB >> 23934138

¹H, ¹⁵N, and ¹³C chemical shift assignments for the winged helix domains of two archeal MCM C-termini.

Christoph Wiedemann1, Oliver Ohlenschläger, Barbara Medagli, Silvia Onesti, Matthias Görlach.   

Abstract

High-fidelity replication guarantees the stable inheritance of genetic information stored in the DNA of living organisms. The minichromosome maintenance (MCM) complex functions as replicative DNA-unwinding helicase and has been identified as one key player in the replication process of archea and eukarya. Despite the availability of considerable structural information on archeal MCMs, such information was missing for their C-terminal domain. In order to obtain more detailed structural information, we assigned the NMR chemical shifts for backbone and side chain nuclei for the MCM C-terminal winged helix domains of the archeal species Methanothermobacter thermautrophicus and Sulfolobus solfataricus.

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Year:  2013        PMID: 23934138     DOI: 10.1007/s12104-013-9516-0

Source DB:  PubMed          Journal:  Biomol NMR Assign        ISSN: 1874-270X            Impact factor:   0.746


  4 in total

1.  An approach to sequential NMR assignments of proteins: application to chemical shift restraint-based structure prediction.

Authors:  Christoph Wiedemann; Peter Bellstedt; Christian Herbst; Matthias Görlach; Ramadurai Ramachandran
Journal:  J Biomol NMR       Date:  2014-06-19       Impact factor: 2.835

2.  Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.

Authors:  Christoph Wiedemann; Anna Szambowska; Sabine Häfner; Oliver Ohlenschläger; Karl-Heinz Gührs; Matthias Görlach
Journal:  Nucleic Acids Res       Date:  2015-02-20       Impact factor: 16.971

3.  Sequential acquisition of multi-dimensional heteronuclear chemical shift correlation spectra with ¹H detection.

Authors:  Peter Bellstedt; Yvonne Ihle; Christoph Wiedemann; Anika Kirschstein; Christian Herbst; Matthias Görlach; Ramadurai Ramachandran
Journal:  Sci Rep       Date:  2014-03-27       Impact factor: 4.379

4.  The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines.

Authors:  Tatjana P Kristensen; Reeja Maria Cherian; Fiona C Gray; Stuart A MacNeill
Journal:  Front Microbiol       Date:  2014-03-26       Impact factor: 5.640

  4 in total

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