Literature DB >> 23933838

[Intraocular lens as a drug delivery device].

K H Eibl-Lindner1, R Liegl, C Wertheimer, A Kampik.   

Abstract

The development of an intraocular lens (IOL) as a drug delivery device has been the purpose of numerous preclinical studies and might become a future technology in cataract surgery. There are three techniques of pharmacological IOL modification: surface modification (coating), optic modification (soaking) or haptic modification with a slow-release-system. The therapeutic goals are endophthalmitis, postoperative inflammation and posterior capsule opacification.

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Year:  2013        PMID： 23933838     DOI： 10.1007/s00347-013-2904-0

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN： 0941-293X            Impact factor:   1.059


  14 in total

1.  Long-term results of sealed capsule irrigation using distilled water to prevent posterior capsule opacification: a prospective clinical randomised trial.

Authors:  Tanja M Rabsilber; Il-Joo Limberger; Andreas J Reuland; Mike P Holzer; Gerd U Auffarth
Journal:  Br J Ophthalmol       Date:  2007-01-03       Impact factor: 4.638

2.  Diamond jubilee of the first intraocular lens implantation?

Authors:  David J Spalton
Journal:  J Cataract Refract Surg       Date:  2009-12       Impact factor: 3.351

3.  Hydrophilic acrylic intraocular lens as a drug delivery system: influence of the presoaking time and comparison to intracameral injection.

Authors:  Inna Lipnitzki; Relli Bronshtein; Shmuel Ben Eliahu; Arie L Marcovich; Guy Kleinmann
Journal:  J Ocul Pharmacol Ther       Date:  2012-12-12       Impact factor: 2.671

4.  Prevention of capsular bag opacification with a modified hydrophilic acrylic disk-shaped intraocular lens.

Authors:  Lisa Leishman; Liliana Werner; Zachary Bodnar; Andrew Ollerton; Jennifer Michelson; Mason Schmutz; Nick Mamalis
Journal:  J Cataract Refract Surg       Date:  2012-07-15       Impact factor: 3.351

5.  Sustained antibiotic release from an intraocular lens-hydrogel assembly for cataract surgery.

Authors:  Shai Garty; Rika Shirakawa; Adelaide Warsen; Erin M Anderson; Misty L Noble; James D Bryers; Buddy D Ratner; Tueng T Shen
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-03       Impact factor: 4.799

6.  A fully human in vitro capsular bag model to permit intraocular lens evaluation.

Authors:  Lucy J Dawes; Christopher D Illingworth; I Michael Wormstone
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-01-03       Impact factor: 4.799

7.  [Prophylaxis and therapy of postoperative endophthalmitis. Criticism of the ESCRS study and the Early Vitrectomy study].

Authors:  W Behrens-Baumann
Journal:  Ophthalmologe       Date:  2011-11       Impact factor: 1.059

8.  Intraocular lens as a drug delivery system for dexamethasone.

Authors:  Maria Kugelberg; Kayvan Shafiei; Ingeborg van der Ploeg; Charlotta Zetterström
Journal:  Acta Ophthalmol       Date:  2009-01-27       Impact factor: 3.761

9.  Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.

Authors: 
Journal:  J Cataract Refract Surg       Date:  2007-06       Impact factor: 3.351

10.  Polylactide-glycoli acid and rapamycin coating intraocular lens prevent posterior capsular opacification in rabbit eyes.

Authors:  Hongling Liu; Lan Wu; Shaoying Fu; Yongsheng Hou; Ping Liu; Hao Cui; Jingjing Liu; Lin Xing; Xiaomei Zhang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-12-09       Impact factor: 3.117
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  3 in total

1.  EGFR inhibitor Gefitinib attenuates posterior capsule opacification in vitro and in the ex vivo human capsular bag model.

Authors:  Christian Wertheimer; Jakob Siedlecki; Daniel Kook; Wolfgang J Mayer; Armin Wolf; Annemarie Klingenstein; Anselm Kampik; Kirsten Eibl-Lindner
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-12-05       Impact factor: 3.117

2.  αVβ8 integrin targeting to prevent posterior capsular opacification.

Authors:  Mahbubul H Shihan; Samuel G Novo; Yan Wang; Dean Sheppard; Amha Atakilit; Thomas D Arnold; Nicole M Rossi; Adam P Faranda; Melinda K Duncan
Journal:  JCI Insight       Date:  2021-11-08

3.  Facile multifunctional IOL surface modification via poly(PEGMA-co-GMA) grafting for posterior capsular opacification inhibition.

Authors:  Jiayi Xia; Duoduo Lu; Yuemei Han; Jiahao Wang; Yueze Hong; Peiyi Zhao; Qiuna Fang; Quankui Lin
Journal:  RSC Adv       Date:  2021-03-08       Impact factor: 3.361
  3 in total

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