| Literature DB >> 2392651 |
S Valdemarsson1, L Edvinsson, P Hedner, R Ekman.
Abstract
Calcitonin gene-related peptide (CGRP) is one of the peptides encoded for by the calcitonin gene. It has been demonstrated in man to be located in the thyroid and in perivascular nerves and to possess potent vasodilatory properties. In the present study we found plasma levels of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) to be significantly higher in females than in males and that women on contraceptive pills had significantly higher CGRP-LI levels than women not taking contraceptives. These data are in accordance with one earlier report on an increased CGRP level during pregnancy and suggest a positive influence of the female sex hormones on the plasma CGRP level in man, which should be considered in the establishment of a reference range for this analysis.Entities:
Keywords: Age Factors; Biology; Comparative Studies; Contraception; Contraceptive Methods; Demographic Factors; Examinations And Diagnoses; Family Planning; Hemic System--analysis; Hemic System--men; Hemic System--women; Laboratory Examinations And Diagnoses; Oral Contraceptives; Physiology; Population; Population Characteristics; Research Methodology; Studies
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Year: 1990 PMID： 2392651 DOI： 10.3109/00365519009091595
Source DB: PubMed Journal: Scand J Clin Lab Invest ISSN： 0036-5513 Impact factor: 1.713