Literature DB >> 239234

3-Substituted 2-formylquinoxaline 1,4-dioxides.

M L Edwards, R E Bambury, H W Ritter.   

Abstract

The methylnitrone of 3-methyl-1,4-dioxidoquinoxaline-2-carboxaldehyde (1) has been exceptional antibacterial activity in vivo. Derivatives of 3-hydroxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde and 3-acetoxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde were prepared. Several of these compounds were found to be antibacterial agents of the same order of activity as I.

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Year:  1975        PMID: 239234     DOI: 10.1021/jm00240a027

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  2 in total

1.  2-Isopropyl-3-methyl-quinoxaline 1,4-dioxide.

Authors:  Jian-Ye Li; Tao Sun; Ai-You Hao; Hongwei Qiao; Feifei Xin
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-07-03

2.  1,2,3,4-Tetra-hydro-phenazine 5,10-dioxide.

Authors:  Tao Sun; Jianye Li; Hongwei Qiao; Aiyou Hao; Yueming Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-08-28
  2 in total

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