| Literature DB >> 239234 |
M L Edwards, R E Bambury, H W Ritter.
Abstract
The methylnitrone of 3-methyl-1,4-dioxidoquinoxaline-2-carboxaldehyde (1) has been exceptional antibacterial activity in vivo. Derivatives of 3-hydroxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde and 3-acetoxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde were prepared. Several of these compounds were found to be antibacterial agents of the same order of activity as I.Entities:
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Year: 1975 PMID: 239234 DOI: 10.1021/jm00240a027
Source DB: PubMed Journal: J Med Chem ISSN: 0022-2623 Impact factor: 7.446