Literature DB >> 23919545

The promise of sulfated synthetic small molecules as modulators of glycosaminoglycan function.

Umesh R Desai.   

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Year:  2013        PMID: 23919545     DOI: 10.4155/fmc.13.117

Source DB:  PubMed          Journal:  Future Med Chem        ISSN: 1756-8919            Impact factor:   3.808


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  15 in total

1.  Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins.

Authors:  Nehru Viji Sankaranarayanan; Umesh R Desai
Journal:  Glycobiology       Date:  2014-07-21       Impact factor: 4.313

2.  On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients.

Authors:  Shravan Morla; Nehru Viji Sankaranarayanan; Daniel K Afosah; Megh Kumar; Apparao B Kummarapurugu; Judith A Voynow; Umesh R Desai
Journal:  J Med Chem       Date:  2019-05-28       Impact factor: 7.446

3.  A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.

Authors:  Rami A Al-Horani; Elsamani I Abdelfadiel; Daniel K Afosah; Shravan Morla; Jyothi C Sistla; Bassem Mohammed; Erika J Martin; Masahiro Sakagami; Donald F Brophy; Umesh R Desai
Journal:  J Thromb Haemost       Date:  2019-09-10       Impact factor: 5.824

4.  Inhibition of Herpes Simplex Virus-1 Entry into Human Cells by Nonsaccharide Glycosaminoglycan Mimetics.

Authors:  Rahaman Navaz Gangji; Nehru Viji Sankaranarayanan; James Elste; Rami A Al-Horani; Daniel K Afosah; Rachel Joshi; Vaibhav Tiwari; Umesh R Desai
Journal:  ACS Med Chem Lett       Date:  2018-07-16       Impact factor: 4.345

Review 5.  Sulfated Non-Saccharide Glycosaminoglycan Mimetics as Novel Drug Discovery Platform for Various Pathologies.

Authors:  Daniel K Afosah; Rami A Al-Horani
Journal:  Curr Med Chem       Date:  2020       Impact factor: 4.530

Review 6.  Mechanistic and therapeutic overview of glycosaminoglycans: the unsung heroes of biomolecular signaling.

Authors:  Khushboo Gulati; Krishna Mohan Poluri
Journal:  Glycoconj J       Date:  2015-12-03       Impact factor: 2.916

7.  A Unique Nonsaccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.

Authors:  Rio S Boothello; Nirmita J Patel; Chetna Sharon; Elsamani I Abdelfadiel; Shravan Morla; Donald F Brophy; H Robert Lippman; Umesh R Desai; Bhaumik B Patel
Journal:  Mol Cancer Ther       Date:  2018-10-18       Impact factor: 6.261

8.  Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics.

Authors:  Daniel K Afosah; Rami A Al-Horani; Nehru Viji Sankaranarayanan; Umesh R Desai
Journal:  J Med Chem       Date:  2017-01-05       Impact factor: 7.446

9.  Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.

Authors:  Rami A Al-Horani; Umesh R Desai
Journal:  J Med Chem       Date:  2014-05-29       Impact factor: 7.446

Review 10.  Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders.

Authors:  Rami A Al-Horani; Umesh R Desai
Journal:  Med Res Rev       Date:  2014-03-21       Impact factor: 12.944

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