Literature DB >> 23917083

Obstetric outcomes of patients undergoing total laparoscopic radical trachelectomy for early stage cervical cancer.

Keiko Ebisawa1, Mizuki Takano, Mika Fukuda, Kazuko Fujiwara, Tomonori Hada, Yoshiaki Ota, Shozo Kurotsuchi, Hiroyuki Kanao, Masaaki Andou.   

Abstract

OBJECTIVE: To assess the obstetric outcomes of our total laparoscopic radical trachelectomy (TLRT) cases for early stage cervical cancer.
MATERIALS AND METHODS: A total of 56 patients who underwent TLRT between December 2001 and August 2012 were reviewed retrospectively using clinicopathological, surgical, and follow-up data from patients' medical records.
RESULTS: We performed this operation on 56 patients during the study period. The mean age of these 56 patients was 31.9 years (range 22-42 years). Fifty-three patients' fertility was preserved without requiring post-operative adjuvant treatment. Twenty-five women attempted to conceive, of whom 13 succeeded for a total of 21 pregnancies (52% pregnancy rate). Ten of these 21 pregnancies were the result of assisted reproductive technologies. Of those, 5 resulted in first trimester miscarriages, 2 in second trimester miscarriages, and 13 in live births. Ten pregnancies reached the third trimester. Preterm premature rupture of membranes (8/13, 61.5%) was the most common complication during pregnancy. The rate of preterm delivery was 47.6%. Three patients delivered at 22-28 weeks of gestational age. Two of these babies showed permanent damage: one has cerebral palsy; the other has developmental retardation. One pregnancy is ongoing.
CONCLUSION: TLRT is a useful technique associated with an excellent pregnancy rate in fertility-preserving surgery to treat early stage cervical cancer.
© 2013.

Entities:  

Keywords:  Cervical cancer; Total laparoscopic radical trachelectomy

Mesh:

Year:  2013        PMID: 23917083     DOI: 10.1016/j.ygyno.2013.07.108

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  8 in total

1.  Outcomes of abdominal radical trachelectomy: results of a multicenter prospective cohort study in a Tohoku Gynecologic Cancer Unit.

Authors:  Hideki Tokunaga; Yoh Watanabe; Hitoshi Niikura; Satoru Nagase; Masafumi Toyoshima; Reiji Shiro; Yoshihito Yokoyama; Hideki Mizunuma; Tsuyoshi Ohta; Hiroshi Nishiyama; Takafumi Watanabe; Naoki Sato; Naoto Sato; Toru Sugiyama; Tadao Takano; Fumiaki Takahashi; Nobuo Yaegashi
Journal:  Int J Clin Oncol       Date:  2014-11-14       Impact factor: 3.402

Review 2.  Current state of fertility preservation for adolescent and young adult patients with gynecological cancer.

Authors:  Tatsuru Ohara; Shiho Kuji; Tomo Takenaga; Haruka Imai; Hiraku Endo; Ryo Kanamori; Jun Takeuchi; Yuko Nagasawa; Noriyuki Yokomichi; Haruhiro Kondo; Imari Deura; Akiko Tozawa; Nao Suzuki
Journal:  Int J Clin Oncol       Date:  2021-11-15       Impact factor: 3.402

3.  Fertility-sparing surgery in early-stage cervical cancer: laparoscopic versus abdominal radical trachelectomy.

Authors:  Zuoxi He; Ce Bian; Chuan Xie
Journal:  BMC Womens Health       Date:  2022-06-18       Impact factor: 2.742

4.  Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer.

Authors:  Elvira Brătilă; C P Brătilă; C B Coroleuca
Journal:  Indian J Surg       Date:  2015-09-28       Impact factor: 0.656

Review 5.  Oncologic and obstetrical outcomes with fertility-sparing treatment of cervical cancer: a systematic review and meta-analysis.

Authors:  Qing Zhang; Wenhui Li; Margaux J Kanis; Gonghua Qi; Minghao Li; Xingsheng Yang; Beihua Kong
Journal:  Oncotarget       Date:  2017-07-11

Review 6.  Fertility preservation in women with cervical, endometrial or ovarian cancers.

Authors:  Michael Feichtinger; Kenny A Rodriguez-Wallberg
Journal:  Gynecol Oncol Res Pract       Date:  2016-07-27

7.  Abdominal scar characteristics as a predictor of cervical stenosis after abdominal radical trachelectomy.

Authors:  Xiaoqi Li; Jin Li; Xingzhu Ju; Xiaojun Chen; Xiaohua Wu
Journal:  Oncotarget       Date:  2016-06-21

8.  Menstrual pattern after abdominal radical trachelectomy.

Authors:  Xiaoqi Li; Jin Li; Xingzhu Ju; Zhaoxia Jiang; Xiaojun Chen; Xiaohua Wu
Journal:  Oncotarget       Date:  2017-05-16
  8 in total

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