Literature DB >> 2391432

Affinity distributions of antigen-specific IgG in patients with multiple sclerosis and in patients with viral encephalitis.

R W Luxton1, E J Thompson.   

Abstract

We report a method for displaying the affinity distribution of a polyclonal antibody population using sodium thiocyanate elution followed by an ELISA detection technique. We have used this method to study the affinity distribution of antibodies in samples of CSF and serum from patients with MS, and compared the results to those obtained from patients with viral encephalitis. Patients with MS had predominantly low affinity antibody against a particular antigen whilst patients with a primary viral infection had predominantly high affinity antibody against the causative organism.

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Year:  1990        PMID： 2391432     DOI： 10.1016/0022-1759(90)90199-6

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  14 in total

1.  Intrathecal production of specific IgA antibodies in CNS infections.

Authors:  M Roberg; P Forsberg; A Tegnell; K Ekerfeldt
Journal:  J Neurol       Date:  1995-06       Impact factor: 4.849

Review 2.  Cerebrospinal fluid.

Authors:  E J Thompson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-10       Impact factor: 10.154

3.  Purification and characterization of oligomeric envelope glycoprotein from a primary R5 subtype B human immunodeficiency virus.

Authors:  Indresh K Srivastava; Leonidas Stamatatos; Harold Legg; Elaine Kan; Anne Fong; Stephen R Coates; Louisa Leung; Mark Wininger; John J Donnelly; Jeffrey B Ulmer; Susan W Barnett
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

Review 4.  Primarily chronic and cerebrovascular course of Lyme neuroborreliosis: case reports and literature review.

Authors:  M Wilke; H Eiffert; H J Christen; F Hanefeld
Journal:  Arch Dis Child       Date:  2000-07       Impact factor: 3.791

5.  Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge.

Authors:  Zhiyuan Wen; Ling Ye; Yulong Gao; Lei Pan; Ke Dong; Zhigao Bu; Richard W Compans; Chinglai Yang
Journal:  Antiviral Res       Date:  2009-09-20       Impact factor: 5.970

6.  Cerebellar ataxia associated with anti-glutamic acid decarboxylase autoantibodies.

Authors:  M Vianello; B Tavolato; M Armani; B Giometto
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

Review 7.  Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.

Authors:  M Andersson; J Alvarez-Cermeño; G Bernardi; I Cogato; P Fredman; J Frederiksen; S Fredrikson; P Gallo; L M Grimaldi; M Grønning
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-08       Impact factor: 10.154

8.  Low antibody affinity restricted to the IgA isotype in IgA nephropathy.

Authors:  L Layward; A C Allen; J M Hattersley; S J Harper; J Feehally
Journal:  Clin Exp Immunol       Date:  1994-01       Impact factor: 4.330

9.  Studies of the neutralizing activity and avidity of anti-human immunodeficiency virus type 1 Env antibody elicited by DNA priming and protein boosting.

Authors:  J F Richmond; S Lu; J C Santoro; J Weng; S L Hu; D C Montefiori; H L Robinson
Journal:  J Virol       Date:  1998-11       Impact factor: 5.103

10.  Avidity progression of dietary antibodies in healthy and coeliac children.

Authors:  R Saalman; U I Dahlgren; S P Fällström; L A Hanson; S Ahlstedt; A E Wold
Journal:  Clin Exp Immunol       Date:  2003-11       Impact factor: 4.330
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