BACKGROUND: The independent influence of advanced age on outcomes in contemporary series treated by early cholecystectomy is undetermined. METHODS: Elderly patients, aged 80 years and older, with histology proven acute cholecystitis treated by cholecystectomy on initial presentation between 2005 and 2011 were compared to all others. RESULTS: In total, 411 patients had histologically proven acute cholecystitis, of whom 71 (17%) were aged 80 years and older. Elderly patients were more likely to have ischaemic heart disease, underlying diabetes and chronic renal failure. There was greater conversion from laparoscopic to open surgery in the elderly (21% versus 7%; P = 0.001). Elderly patients were more likely to have gangrenous cholecystitis (44% versus 31%; P = 0.033) and common bile duct stones (27% versus 17%; P = 0.048). Elderly patients had more complications (31% versus 13%; P < 0.001), a higher mortality rate (4% versus 1%; P = 0.038) and a longer median post-operative length of stay (7 days versus 3 days; P < 0.001). Age ≥ 80 (P = 0.004) was an independent risk factors for complications. CONCLUSION: Age 80 years and older is independently associated with increased morbidity following cholecystectomy for treatment acute cholecystitis at initial presentation.
BACKGROUND: The independent influence of advanced age on outcomes in contemporary series treated by early cholecystectomy is undetermined. METHODS: Elderly patients, aged 80 years and older, with histology proven acute cholecystitis treated by cholecystectomy on initial presentation between 2005 and 2011 were compared to all others. RESULTS: In total, 411 patients had histologically proven acute cholecystitis, of whom 71 (17%) were aged 80 years and older. Elderly patients were more likely to have ischaemic heart disease, underlying diabetes and chronic renal failure. There was greater conversion from laparoscopic to open surgery in the elderly (21% versus 7%; P = 0.001). Elderly patients were more likely to have gangrenous cholecystitis (44% versus 31%; P = 0.033) and common bile duct stones (27% versus 17%; P = 0.048). Elderly patients had more complications (31% versus 13%; P < 0.001), a higher mortality rate (4% versus 1%; P = 0.038) and a longer median post-operative length of stay (7 days versus 3 days; P < 0.001). Age ≥ 80 (P = 0.004) was an independent risk factors for complications. CONCLUSION: Age 80 years and older is independently associated with increased morbidity following cholecystectomy for treatment acute cholecystitis at initial presentation.
Authors: Alfredo Escartín; Marta González; Elena Cuello; Ana Pinillos; Pablo Muriel; Mireia Merichal; Victor Palacios; Jordi Escoll; Cristina Gas; Jorge-Juan Olsina Journal: Surg Res Pract Date: 2019-02-03
Authors: Charlotte S Loozen; Hjalmar C van Santvoort; Peter van Duijvendijk; Marc Gh Besselink; Dirk J Gouma; Grard Ap Nieuwenhuijzen; Johannes C Kelder; Sandra C Donkervoort; Anna Aw van Geloven; Philip M Kruyt; Daphne Roos; Kirsten Kortram; Verena Nn Kornmann; Apollo Pronk; Donald L van der Peet; Rogier Mph Crolla; Bert van Ramshorst; Thomas L Bollen; Djamila Boerma Journal: BMJ Date: 2018-10-08
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Authors: Dragos Serban; Bogdan Socea; Simona Andreea Balasescu; Cristinel Dumitru Badiu; Corneliu Tudor; Ana Maria Dascalu; Geta Vancea; Radu Iulian Spataru; Alexandru Dan Sabau; Dan Sabau; Ciprian Tanasescu Journal: Medicina (Kaunas) Date: 2021-03-02 Impact factor: 2.430