Literature DB >> 239100

Effect of ornithine alpha oxoglutarate on brain metabolism in patients with chronic liver disease.

I M James, A N Hamlyn, P C Brant, P Hildrew.   

Abstract

Patients with chronic liver disease, yet without severe encephalopathy, were found to show evidence of increased brain utilization of glucose. The changes were abolished after an intravenous infusion of 15 g ornithine alpha oxoglutarate, given over a period of 15 minutes. The possible implications of these observations are discussed.

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Year:  1975        PMID： 239100      PMCID： PMC491898          DOI： 10.1136/jnnp.38.3.214

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  16 in total

1.  QUANTITATIVE CEREBRAL BLOOD FLOW DETERMINATION. APPLICATION OF A KRYPTON 85 DESATURATION TECHNIQUE IN MAN.

Authors:  L C MCHENRY
Journal:  Neurology       Date:  1964-09       Impact factor: 9.910

2.  SIMPLE METHODS FOR THE DETERMINATION OF THE CONCENTRATIONS OF CARBON DIOXIDE AND OXYGEN IN BLOOD.

Authors:  R J LINDEN; J R LEDSOME; J NORMAN
Journal:  Br J Anaesth       Date:  1965-02       Impact factor: 9.166

3.  CEREBRAL CARBOHYDRATE METABOLISM DURING HYPOCARBIA IN MAN: STUDIES DURING NITROUS OXIDE ANESTHESIA.

Authors:  S C ALEXANDER; P J COHEN; H WOLLMAN; T C SMITH; M REIVICH; R A VANDERMOLEN
Journal:  Anesthesiology       Date:  1965 Sep-Oct       Impact factor: 7.892

4.  The cerebral and peripheral uptake of ammonia in liver disease with an hypothesis for the mechanism of hepatic coma.

Authors:  S P BESSMAN; A N BESSMAN
Journal:  J Clin Invest       Date:  1955-04       Impact factor: 14.808

5.  Ammonia toxicity and cerebral oxidative metabolism.

Authors:  G M MCKHANN; D B TOWER
Journal:  Am J Physiol       Date:  1961-03

6.  Cerebral metabolism in hepatic insufficiency.

Authors:  R W ALMAN; W R EHRMANTRAUT; J F FAZEKAS; H E TICKTIN
Journal:  Am J Med       Date:  1956-12       Impact factor: 4.965

7.  THEORY OF THE USE OF ARTERIOVENOUS CONCENTRATION DIFFERENCES FOR MEASURING METABOLISM IN STEADY AND NON-STEADY STATES.

Authors:  K L Zierler
Journal:  J Clin Invest       Date:  1961-12       Impact factor: 14.808

8.  Cerebral metabolism after portacaval shunt.

Authors:  E Polli; G Bianchi Porro; A T Maiolo
Journal:  Lancet       Date:  1969-01-18       Impact factor: 79.321

9.  Effect of ammonium salts on brain metabolism.

Authors:  I M James; L MacDonnell; C Xanalatos
Journal:  J Neurol Neurosurg Psychiatry       Date:  1974-08       Impact factor: 10.154

10.  Treatment of chronic hepatic encephalopathy with levodopa.

Authors:  M Lunzer; I M James; J Weinman; S Sherlock
Journal:  Gut       Date:  1974-07       Impact factor: 23.059
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