| Literature DB >> 23903550 |
Christine White1, Helen Keegan, Loretto Pilkington, Carmel Ruttle, Patrick Kerr, Linda Sharp, Sharon O'Toole, Michael Turner, Walter Prendiville, Tom D'Arcy, Myra Fitzpatrick, Peter Lenehan, Grainne Flannelly, John J O'Leary, Cara M Martin.
Abstract
The clinical performance of the cobas human papillomavirus (HPV) test for detection of high-grade disease in a colposcopy-referred population was compared with that of Hybrid Capture 2 (HC2). The overall agreement between the tests was 92.3%. Clinical sensitivity and specificity for detection of cervical intraepithelial neoplasia grade 2 or greater (CIN2+) were 90.0% and 55.5% for cobas and 90.5% and 50.2% for HC2, respectively. In conclusion, both tests showed comparable performance for detection of CIN2+.Entities:
Mesh:
Year: 2013 PMID: 23903550 PMCID: PMC3811647 DOI: 10.1128/JCM.01949-13
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948