Literature DB >> 23900506

Three-dimensional variability of the mesentery and the superior mesenteric artery: application to virtual trauma modeling.

Damien Massalou1, Thierry Bège, Stéphane Bourgouin, Julien Mancini, Catherine Masson, Patrick Baqué, Stéphane-Victor Berdah.   

Abstract

INTRODUCTION: Trauma is a major cause of death worldwide, mainly affecting a young male population. Blunt trauma of the abdomen can cause a trauma of the mesentery in 5 % of cases. Rapid decelerations and injuries by seat belts are the most common pathophysiological mechanisms. Three-dimensional anatomical scanning of the mesentery and gastrointestinal tract is the first essential step in modeling abdominal trauma in an attempt to understand the pathophysiology of mesenteric lesions and to improve the safety features of vehicles. OBJECTIVE OF THE STUDY: To analyze the individual variability of the mesentery and the superior mesenteric artery (SMA) from medical imaging and to develop a three-dimensional customizable finite element model.
MATERIALS AND METHODS: In this retrospective study, one hundred abdominopelvic injected CT scans were analyzed from healthy patients. The evaluation criteria of the mesentery were its volume (total and the distribution of adipose tissue/non adipose tissue), the length of the SMA and the distance between duodenojejunal angle (DJA) and the ileocecal junction (ICJ). The variability of these measures has been studied by demographic (age and gender) and morphologic (height evaluated by the T11-L4 distance, the waist circumference and the thickness of the subcutaneous adipose tissue).
RESULTS: Mean mesenteric volume was 644 cm(3) (ranges from 89 to 1,869 cm(3)), and the mean length of the SMA was 224.9 mm (ranges from 138.4 to 312.3). There was a statistically significant association between waist circumference and the total volume of the mesentery, its fat component and non fat component (p < 0.001). Waist circumference was the only morphological parameter associated with the length of the superior mesenteric artery and the length of the DJA to ICJ (p < 0.001). Subcutaneous adipose tissue and female sex were statistically associated with total mesentery volume (respectively, p = 0.005 and p = 0.001). Age was an independent predictor of the increased volume of the mesentery and the length of the SMA. The height of the subject changes the length of the SMA (p = 0.001).
CONCLUSION: The assessment of the mesenteric variability highlighted three factors associated with its size and length: age, sex, and waist circumference. These parameters have to be taken into account to personalize numerical model in the area of virtual trauma.

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Year:  2013        PMID: 23900506     DOI: 10.1007/s00276-013-1178-1

Source DB:  PubMed          Journal:  Surg Radiol Anat        ISSN: 0930-1038            Impact factor:   1.246


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