PURPOSE: Studies have reported an association between hospital volume and survival for non-small-cell lung cancer (NSCLC). We explored this association in England, accounting for case mix and propensity to resect. METHODS: We analyzed data on 134,293 patients with NSCLC diagnosed in England between 2004 and 2008, of whom 12,862 (9.6%) underwent surgical resection. Hospital volume was defined according to number of patients with resected lung cancer in each hospital in each year of diagnosis. We calculated hazard ratios (HRs) for death in three predefined periods according to hospital volume, sex, age, socioeconomic deprivation, comorbidity, and propensity to resect. RESULTS: There was increased survival in hospitals performing > 150 surgical resections compared with those carrying out < 70 (HR, 0.78; 95% CI, 0.67 to 0.90; Ptrend < .01). The association between hospital volume and survival was present in all three periods of follow-up, but the magnitude of association was greatest in the early postoperative period. CONCLUSION: High-volume hospitals have higher resection rates and perform surgery among patients who are older, have lower socioeconomic status, and have more comorbidities; despite this, they achieve better survival, most notably in the early postoperative period.
PURPOSE: Studies have reported an association between hospital volume and survival for non-small-cell lung cancer (NSCLC). We explored this association in England, accounting for case mix and propensity to resect. METHODS: We analyzed data on 134,293 patients with NSCLC diagnosed in England between 2004 and 2008, of whom 12,862 (9.6%) underwent surgical resection. Hospital volume was defined according to number of patients with resected lung cancer in each hospital in each year of diagnosis. We calculated hazard ratios (HRs) for death in three predefined periods according to hospital volume, sex, age, socioeconomic deprivation, comorbidity, and propensity to resect. RESULTS: There was increased survival in hospitals performing > 150 surgical resections compared with those carrying out < 70 (HR, 0.78; 95% CI, 0.67 to 0.90; Ptrend < .01). The association between hospital volume and survival was present in all three periods of follow-up, but the magnitude of association was greatest in the early postoperative period. CONCLUSION: High-volume hospitals have higher resection rates and perform surgery among patients who are older, have lower socioeconomic status, and have more comorbidities; despite this, they achieve better survival, most notably in the early postoperative period.
Authors: Ryan C Broderick; Hans F Fuchs; Cristina R Harnsberger; David C Chang; Elisabeth McLemore; Sonia Ramamoorthy; Santiago Horgan Journal: Surg Endosc Date: 2014-08-27 Impact factor: 4.584
Authors: Ryan C Broderick; Hans F Fuchs; Cristina R Harnsberger; David C Chang; Bryan J Sandler; Garth R Jacobsen; Santiago Horgan Journal: Obes Surg Date: 2015-12 Impact factor: 4.129
Authors: Alba A Brandes; Enrico Franceschi; Mario Ermani; Alicia Tosoni; Fiorenzo Albani; Roberta Depenni; Marina Faedi; Anna Pisanello; Girolamo Crisi; Benedetta Urbini; Claudio Dazzi; Luigi Cavanna; Claudia Mucciarini; Giuseppe Pasini; Stefania Bartolini; Gianluca Marucci; Luca Morandi; Elena Zunarelli; Serenella Cerasoli; Giorgio Gardini; Giovanni Lanza; Enrico Maria Silini; Silvio Cavuto; Agostino Baruzzi; A Baruzzi; F Albani; F Calbucci; R D'Alessandro; R Michelucci; A Brandes; V Eusebi; S Ceruti; E Fainardi; R Tamarozzi; E Emiliani; M Cavallo; E Franceschi; A Tosoni; M Cavallo; F Fiorica; A Valentini; R Depenni; C Mucciarini; G Crisi; E Sasso; C Biasini; L Cavanna; D Guidetti; N Marcello; A Pisanello; A M Cremonini; G Guiducci; S de Pasqua; S Testoni; R Agati; G Ambrosetto; A Bacci; E Baldin; A Baldrati; E Barbieri; S Bartolini; E Bellavista; F Bisulli; E Bonora; F Bunkheila; V Carelli; M Crisci; P Dall'Occa; D de Biase; S Ferro; C Franceschi; G Frezza; V Grasso; M Leonardi; G Marucci; V Mazzocchi; L Morandi; B Mostacci; G Palandri; E Pasini; M Pastore Trossello; A Pession; M Ragazzi; P Riguzzi; R Rinaldi; S Rizzi; G Romeo; F Spagnolli; P Tinuper; C Trocino; S Cerasoli; M Dall'Agata; M Faedi; M Frattarelli; G Gentili; A Giovannini; P Iorio; U Pasquini; G Galletti; C Guidi; W Neri; A Patuelli; S Strumia; M Casmiro; A Gamboni; F Rasi; G Cruciani; P Cenni; C Dazzi; Ar Guidi; F Zumaglini; A Amadori; G Pasini; M Pasquinelli; E Pasquini; A Polselli; A Ravasio; B Viti; M Sintini; A Ariatti; F Bertolini; G Bigliardi; P Carpeggiani; F Cavalleri; S Meletti; P Nichelli; E Pettorelli; G Pinna; E Zunarelli; F Artioli; I Bernardini; M Costa; G Greco; R Guerzoni; C Stucchi; C Iaccarino; R Rizzi; G Zuccoli; P Api; F Cartei; E Fallica; E Granieri; F Latini; G Lelli; C Monetti; V Ramponi; A Saletti; R Schivalocchi; S Seraceni; M R Tola; B Urbini; C Giorgi; E Montanari; D Cerasti; P Crafa; I Dascola; I Florindo; S Mazza; F Servadei; Em Silini; P Torelli; P Immovilli; N Morelli; C Vanzo Journal: Neurooncol Pract Date: 2014-08-28
Authors: Alan D L Sihoe; Baohui Han; Timothy Y Yang; Changqing Pan; Gening Jiang; Vincent W T Fang Journal: World J Surg Date: 2017-11 Impact factor: 3.352
Authors: Jennifer J Wilkes; Sean Hennessy; Rui Xiao; Susan Rheingold; Alix E Seif; Yuan-Shung Huang; Neika Vendetti; Yimei Li; Rochelle Bagatell; Richard Aplenc; Brian T Fisher Journal: Clin Lymphoma Myeloma Leuk Date: 2016-05-04
Authors: Evan J Wuthrick; Qiang Zhang; Mitchell Machtay; David I Rosenthal; Phuc Felix Nguyen-Tan; André Fortin; Craig L Silverman; Adam Raben; Harold E Kim; Eric M Horwitz; Nancy E Read; Jonathan Harris; Qian Wu; Quynh-Thu Le; Maura L Gillison Journal: J Clin Oncol Date: 2014-12-08 Impact factor: 44.544