Literature DB >> 23895095

Thiourea and guanidine derivatives as antimalarial and antimicrobial agents.

Amita Mishra1, Sanjay Batra.   

Abstract

Thiourea and guanidine substructural units are of significant importance as the compounds containing these core units either in the open or the cyclic form are known to display an array of pharmacological properties. This brief review assimilates the literature on the medicinal significance of thiourea and guanidine derivatives with respect to antimalarial and antimicrobial activities.

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Year:  2013        PMID： 23895095     DOI： 10.2174/15680266113139990126

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  9 in total

1.  Mitochondria-targeted Re(I) complexes bearing guanidinium as ligands and their anticancer activity.

Authors:  Shu-Fen He; Nan-Lian Pan; Bing-Bing Chen; Jia-Xin Liao; Min-Ying Huang; Hai-Jun Qiu; Dong-Chun Jiang; Jun-Jie Wang; Jia-Xi Chen; Jing Sun
Journal:  J Biol Inorg Chem       Date:  2020-10-20       Impact factor: 3.358

2.  Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its in silico and in vitro investigations for RNR, DNA binding, urease inhibition and radical scavenging activities.

Authors:  Aqsa Khalid; Nasima Arshad; Pervaiz Ali Channar; Aamer Saeed; Muhammad Ismail Mir; Qamar Abbas; Syeda Abida Ejaz; Tuncer Hökelek; Amna Saeed; Arfa Tehzeeb
Journal:  RSC Adv       Date:  2022-06-10       Impact factor: 4.036

3.  Synthesis and Structural Characterization of 1-Arylimidazole-2-thiones and N,N'-Aryldiethoxyethylthioureas with Electronically Diverse Substituents: A Manifold of Hydrogen Bonding Networks.

Authors:  Joshua H Palmer; Gerard Parkin
Journal:  New J Chem       Date:  2014-09-01       Impact factor: 3.591

Review 4.  Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas.

Authors:  Amr El-Demerdash; Atanas G Atanasov; Anupam Bishayee; Mamdouh Abdel-Mogib; John N A Hooper; Ali Al-Mourabit
Journal:  Nutrients       Date:  2018-01-02       Impact factor: 5.717

5.  N-Naphthoyl Thiourea Derivatives: An Efficient Ultrasonic-Assisted Synthesis, Reaction, and In Vitro Anticancer Evaluations.

Authors:  Wael Abdelgayed Ahmed Arafa; Amira Atef Ghoneim; Asmaa K Mourad
Journal:  ACS Omega       Date:  2022-02-09

6.  Guanidine-Curcumin Complex-Loaded Amine-Functionalised Hollow Mesoporous Silica Nanoparticles for Breast Cancer Therapy.

Authors:  Thimma Mohan Viswanathan; Kaniraja Chitradevi; Azar Zochedh; Ramakrishnan Vijayabhaskar; Sureba Sukumaran; Selvaraj Kunjiappan; Nachimuthu Senthil Kumar; Krishnan Sundar; Ewa Babkiewicz; Piotr Maszczyk; Thandavarayan Kathiresan
Journal:  Cancers (Basel)       Date:  2022-07-18       Impact factor: 6.575

7.  Anticancer activity and QSAR study of sulfur-containing thiourea and sulfonamide derivatives.

Authors:  Ratchanok Pingaew; Veda Prachayasittikul; Apilak Worachartcheewan; Anusit Thongnum; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Journal:  Heliyon       Date:  2022-08-02

8.  Investigation of the reactivity properties of a thiourea derivative with anticancer activity by DFT and MD simulations.

Authors:  Y Sheena Mary; Y Shyma Mary; Anna Bielenica; Stevan Armaković; Sanja J Armaković; Vivek Chandramohan; Manjunath Dammalli
Journal:  J Mol Model       Date:  2021-07-03       Impact factor: 1.810

9.  Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species.

Authors:  Aamer Saeed; Alejandra Bosch; Marisa Bettiol; Diana L Nossa González; Mauricio Federico Erben; Yanina Lamberti
Journal:  Molecules       Date:  2018-05-11       Impact factor: 4.411
  9 in total

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