Literature DB >> 23893272

Bleeding from oesophageal varices in pregnancy.

Marta Sobral1, Carla Granja, Margarida Sampaio, Fernando Guerreiro.   

Abstract

Bleeding from oesophageal varices is the most fearful event in pregnant women with cirrhosis and is the main cause of death in this group. Its approach and treatment are controversial, with ligation, sclerosis and β-blockers as possible choices. Follow-up must be multidisciplinary and delivery programmed because of the high risk of bleeding. Delivery route is also controversial. We present a case of a pregnant woman, with alcoholic cirrhosis and upper tract bleeding during the second trimester of pregnancy. She was submitted to an oesophagogastroduodenoscopy (OGD), which revealed varices grade II/III in the lower third of the oesophagus. She was transfused and was haemodynamically stable. It was decided not to start β-blockers. The pregnancy went well, with regular follow-up in obstetrics and hepatology. A deficiency of α-1 antitrypsin was detected. Delivery was programmed at 39 weeks of gestation, and a caesarean section was performed, with good maternal and fetal outcome.

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Mesh:

Year:  2013        PMID: 23893272      PMCID: PMC3736262          DOI: 10.1136/bcr-2013-009653

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

Review 1.  Endoscopy in pregnancy.

Authors:  Seamus O'mahony
Journal:  Best Pract Res Clin Gastroenterol       Date:  2007       Impact factor: 3.043

Review 2.  Pregnancy and cirrhosis.

Authors:  Jennifer Tan; Bijal Surti; Sammy Saab
Journal:  Liver Transpl       Date:  2008-08       Impact factor: 5.799

3.  Elective forceps delivery and extradural anaesthesia in a primigravida with portal hypertension and oesophageal varices.

Authors:  J A Heriot; C M Steven; R S Sattin
Journal:  Br J Anaesth       Date:  1996-02       Impact factor: 9.166

4.  Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency.

Authors:  Christopher L Bowlus; Ira Willner; Mark A Zern; Adrian Reuben; Philip Chen; Brian Holladay; Lianqi Xie; Robert F Woolson; Charlie Strange
Journal:  Clin Gastroenterol Hepatol       Date:  2005-04       Impact factor: 11.382

Review 5.  Liver disease in alpha 1-antitrypsin deficiency: a review.

Authors:  Kyrsten D Fairbanks; Anthony S Tavill
Journal:  Am J Gastroenterol       Date:  2008-08       Impact factor: 10.864

Review 6.  Cirrhosis and portal hypertension in pregnancy.

Authors:  M A Russell; S D Craigo
Journal:  Semin Perinatol       Date:  1998-04       Impact factor: 3.300

Review 7.  Liver disease in pregnancy.

Authors:  Noel M Lee; Carla W Brady
Journal:  World J Gastroenterol       Date:  2009-02-28       Impact factor: 5.742

Review 8.  Liver disease in pregnancy.

Authors:  J Eileen Hay
Journal:  Hepatology       Date:  2008-03       Impact factor: 17.425

  8 in total
  2 in total

1.  Successful pregnancy with autoimmune cirrhosis.

Authors:  António Braga; Jorge Braga
Journal:  BMJ Case Rep       Date:  2016-01-29

2.  Upper Gastrointestinal Bleeding in Pregnancy: An Unexpected Cause.

Authors:  Sweta Khuraijam; Varsha Shinde; Amol S Dahale
Journal:  J Emerg Trauma Shock       Date:  2022-04-04
  2 in total

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