Literature DB >> 23891098

Inter-observer variation in delineation of the heart and left anterior descending coronary artery in radiotherapy for breast cancer: a multi-centre study from Denmark and the UK.

Ebbe L Lorenzen1, Carolyn W Taylor, Maja Maraldo, Mette H Nielsen, Birgitte V Offersen, Maria R Andersen, Dean O'Dwyer, Lone Larsen, Sharon Duxbury, Baljit Jhitta, Sarah C Darby, Marianne Ewertz, Carsten Brink.   

Abstract

BACKGROUND AND
PURPOSE: To determine the extent of inter-observer variation in delineation of the heart and left anterior descending coronary artery (LADCA) and its impact on estimated doses. METHODS AND MATERIALS: Nine observers from five centres delineated the heart and LADCA on fifteen patients receiving left breast radiotherapy. The delineations were carried out twice, first without guidelines and then with a set of common guidelines.
RESULTS: For the heart, most spatial variation in delineation was near the base of the heart whereas for the LADCA most variation was in its length at the apex of the heart. Common guidelines reduced the spatial variation for the heart and the length of the LAD, but increased the variation in the anterior-posterior/right-left plane. The coefficients of variation (CV) in the estimated doses to the heart were: mean dose 7.5% without and 3.6% with guidelines, maximum dose 8.7% without and 4.0% with guidelines. The CVs in the estimated doses to the LADCA were: mean dose 27% without and 29% with guidelines, maximum dose 39% without and 31% with guidelines.
CONCLUSIONS: For the heart, there was little inter-observer variation in the estimated dose, especially when guidelines were used. In contrast, for the LADCA there was substantial variation in the estimated dose, which was not reduced with guidelines.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Breast cancer radiotherapy; Delineation; Heart dose; Inter-observer variation; Left anterior descending coronary artery

Mesh:

Year:  2013        PMID: 23891098     DOI: 10.1016/j.radonc.2013.06.025

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  30 in total

1.  Assessment of a guideline-based heart substructures delineation in left-sided breast cancer patients undergoing adjuvant radiotherapy : Quality assessment within a randomized phase III trial testing a cardioprotective treatment strategy (SAFE-2014).

Authors:  Giulio Francolini; Isacco Desideri; Icro Meattini; Carlotta Becherini; Francesca Terziani; Emanuela Olmetto; Camilla Delli Paoli; Donato Pezzulla; Mauro Loi; Pierluigi Bonomo; Daniela Greto; Silvia Calusi; Marta Casati; Stefania Pallotta; Lorenzo Livi
Journal:  Strahlenther Onkol       Date:  2018-11-07       Impact factor: 3.621

2.  Spatial orientation of coronary arteries and its implication for breast and thoracic radiotherapy-proposing "coronary strip" as a new organ at risk.

Authors:  Anusheel Munshi; Nilaxi Khataniar; Biplab Sarkar; Moti Lal Bera; Bidhu Kalyan Mohanti
Journal:  Strahlenther Onkol       Date:  2018-04-12       Impact factor: 3.621

3.  Selection of patients with left breast cancer for deep-inspiration breath-hold radiotherapy technique: Results of a prospective study.

Authors:  Beata Czeremszyńska; Stanisław Drozda; Michał Górzyński; Lucyna Kępka
Journal:  Rep Pract Oncol Radiother       Date:  2017-06-30

4.  Comparing four radiotherapy techniques for treating the chest wall plus levels III-IV draining nodes after breast reconstruction.

Authors:  Valentina Lancellotta; Martina Iacco; Elisabetta Perrucci; Lorenzo Falcinelli; Claudio Zucchetti; Berardino de Bari; Simonetta Saldi; Cynthia Aristei
Journal:  Br J Radiol       Date:  2018-03-19       Impact factor: 3.039

5.  Sparing Cardiac Substructures With Optimized Volumetric Modulated Arc Therapy and Intensity Modulated Proton Therapy in Thoracic Radiation for Locally Advanced Non-small Cell Lung Cancer.

Authors:  Matthew J Ferris; Katherine S Martin; Jeffrey M Switchenko; Oluwatosin A Kayode; Jonathan Wolf; Quang Dang; Robert H Press; Walter J Curran; Kristin A Higgins
Journal:  Pract Radiat Oncol       Date:  2019-05-09

6.  Contouring variations and the role of atlas in non-small cell lung cancer radiation therapy: Analysis of a multi-institutional preclinical trial planning study.

Authors:  Yunfeng Cui; Wenzhou Chen; Feng-Ming Spring Kong; Lindsey A Olsen; Ronald E Beatty; Peter G Maxim; Timothy Ritter; Jason W Sohn; Jane Higgins; James M Galvin; Ying Xiao
Journal:  Pract Radiat Oncol       Date:  2014-06-30

Review 7.  Cardiac Toxicity after Radiotherapy for Breast Cancer: Myths and Facts.

Authors:  Mirko Nitsche; René Pahl; Karen Huber; Kirsten Eilf; Juergen Dunst
Journal:  Breast Care (Basel)       Date:  2015-04       Impact factor: 2.860

8.  Does mean heart dose sufficiently reflect coronary artery exposure in left-sided breast cancer radiotherapy? : Influence of respiratory gating.

Authors:  Martina Becker-Schiebe; Maxi Stockhammer; Wolfgang Hoffmann; Fabian Wetzel; Heiko Franz
Journal:  Strahlenther Onkol       Date:  2016-07-07       Impact factor: 3.621

9.  Left-sided Breast Cancer Irradiation With Deep Inspiration Breath-hold: Changes in Heart and Lung Dose in Two Periods.

Authors:  Anne Caroline Knöchelmann; Nese Ceylan; Michael Bremer
Journal:  In Vivo       Date:  2022 Jan-Feb       Impact factor: 2.155

10.  A slice classification model-facilitated 3D encoder-decoder network for segmenting organs at risk in head and neck cancer.

Authors:  Shuming Zhang; Hao Wang; Suqing Tian; Xuyang Zhang; Jiaqi Li; Runhong Lei; Mingze Gao; Chunlei Liu; Li Yang; Xinfang Bi; Linlin Zhu; Senhua Zhu; Ting Xu; Ruijie Yang
Journal:  J Radiat Res       Date:  2021-01-01       Impact factor: 2.724

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.