[Simplified intraarterial infusion and angiographic method for rabbit VX-2 hind limb tumor via the saphenous artery].

We developed a new simplified intraarterial infusion and angiographic method for rabbit VX-2 hind limb tumors. A 24 gauge cannula was placed in the saphenous artery of the tumor-bearing leg (not supplying the tumor) and used for intraarterial drug infusion or angiography. This method has several advantages as follows: 1) easy and time-saving in manipulation (about 15 minutes per a rabbit); 2) selective drug infusion into the tumor-supplying artery without fluoroscopy; 3) sequential follow-up angiographies available for weeks.