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Literature DB >> 23877696

Genetic characterization and emergence of the metallo-β-lactamase GIM-1 in Pseudomonas spp. and Enterobacteriaceae during a long-term outbreak.

Andreas F Wendel¹, Alexander H B Brodner, Stephan Wydra, Sofija Ressina, Birgit Henrich, Klaus Pfeffer, Mark A Toleman, Colin R Mackenzie.

Abstract

Since the first isolation in 2002, the metallo-β-lactamase GIM-1 has not been detected outside Germany. The data presented here, for 50 clinical blaGIM-1-positive isolates, including Pseudomonas spp. and Enterobacteriaceae (Enterobacter cloacae, Klebsiella oxytoca, Serratia marcescens, Escherichia coli, and Citrobacter freundii), collected between 2007 and 2012 at the original site in an ongoing outbreak, demonstrate a diverse genetic background and dissemination of the gene conferring resistance to enteric bacteria.

Entities: Chemical

Mesh：

Substances：
beta-Lactamases

Year: 2013 PMID： 23877696 PMCID： PMC3811479 DOI： 10.1128/AAC.00118-13

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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