Literature DB >> 2387767

Isolation, characterization and structures of PA-46101 A and B.

M Matsumoto1, Y Kawamura, Y Yoshimura, Y Terui, H Nakai, T Yoshida, J Shoji.   

Abstract

New antibiotics, PA-46101 A and B, were isolated from the culture broth of a Streptomycete. The molecular formulae of A and B were determined to be C52H70O18 and C61H86O22, respectively, by elemental analyses, NMR and mass spectrometry. Their structures were elucidated by X-ray crystallography and NMR spectroscopy. These antibiotics are active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria.

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Year:  1990        PMID: 2387767     DOI: 10.7164/antibiotics.43.739

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  5 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Microwave-assisted multicomponent reaction in water leading to highly regioselective formation of benzo[f]azulen-1-ones.

Authors:  Shu-Liang Wang; Chuang Cheng; Fei-Yue Wu; Bo Jiang; Feng Shi; Shu-Jiang Tu; Trideep Rajale; Guigen Li
Journal:  Tetrahedron       Date:  2011-06-24       Impact factor: 2.457

3.  Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.

Authors:  Hua Zhang; Jess A White-Phillip; Charles E Melançon; Hyung-jin Kwon; Wei-luen Yu; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2007-11-07       Impact factor: 15.419

Review 4.  Spirotetronate polyketides as leads in drug discovery.

Authors:  Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  J Nat Prod       Date:  2014-12-01       Impact factor: 4.050

5.  Phocoenamicins B and C, New Antibacterial Spirotetronates Isolated from a Marine Micromonospora sp.

Authors:  Mercedes Pérez-Bonilla; Daniel Oves-Costales; Mercedes de la Cruz; Maria Kokkini; Jesús Martín; Francisca Vicente; Olga Genilloud; Fernando Reyes
Journal:  Mar Drugs       Date:  2018-03-16       Impact factor: 5.118

  5 in total

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