INTRODUCTION: Despite encouraging short-term and mid-term results, transcatheter aortic valve implantation (TAVI) interventions are still burdened from high rates of adverse events, stressing the need for accurate predictive risk instruments. We compared available surgical risk scores to describe unfavorable outcomes after TAVI. METHODS: The Age, Creatinine, and Ejection fraction (ACEF) score, the logistic Euroscore, and the Society of Thoracic Surgeons Mortality score (STS) were appraised for their independent power of prediction and for their accuracy (C-index) to predict 30-day and medium-term mortality, according to the Valve Academic Research Consortium. RESULTS: Nine hundred and sixty-two patients were included. All the scores demonstrated a moderate positive correlation. The closest correlation was observed between the STS score and Euroscore. After logistic regression analysis, STS score and Logistic Euroscore provided independent prediction for short-term all-cause mortality [P = 0.02, odds ratio (OR) 1.1; 95% confidence interval (CI) 1.06-1.31 and P = 0.027, OR 1.03; 95% CI 1.01-1.405]. For in-hospital complications, only STS score performed significantly (P = 0.005, OR 1.05; 95% CI 1.01-1.06). ACEF, Euroscore, and STS score showed low accuracy for 30-day all-cause mortality (area under the curve 0.6, 0.44-0.75; vs. 0.53, 0.42-0.61; vs. 0.62, 0.52-0.71, respectively), whereas STS score performed better for in-hospital complications (0.59, 0.55-0.64). Moreover, after Cox-multivariate adjustments, only ACEF score was near to significance to predict all-cause mortality at mid-term (OR 1.7; 0.8-2.9; P = 0.058), showing the highest accuracy (0.63, 0.55-0.71). CONCLUSION: In TAVI patients, ACEF score, STS score and Logistic Euroscore provided only a moderate correlation and a low accuracy both for 30-day and medium-term outcomes. Dedicated scores are needed to properly tailor time and kind of approach.
INTRODUCTION: Despite encouraging short-term and mid-term results, transcatheter aortic valve implantation (TAVI) interventions are still burdened from high rates of adverse events, stressing the need for accurate predictive risk instruments. We compared available surgical risk scores to describe unfavorable outcomes after TAVI. METHODS: The Age, Creatinine, and Ejection fraction (ACEF) score, the logistic Euroscore, and the Society of Thoracic Surgeons Mortality score (STS) were appraised for their independent power of prediction and for their accuracy (C-index) to predict 30-day and medium-term mortality, according to the Valve Academic Research Consortium. RESULTS: Nine hundred and sixty-two patients were included. All the scores demonstrated a moderate positive correlation. The closest correlation was observed between the STS score and Euroscore. After logistic regression analysis, STS score and Logistic Euroscore provided independent prediction for short-term all-cause mortality [P = 0.02, odds ratio (OR) 1.1; 95% confidence interval (CI) 1.06-1.31 and P = 0.027, OR 1.03; 95% CI 1.01-1.405]. For in-hospital complications, only STS score performed significantly (P = 0.005, OR 1.05; 95% CI 1.01-1.06). ACEF, Euroscore, and STS score showed low accuracy for 30-day all-cause mortality (area under the curve 0.6, 0.44-0.75; vs. 0.53, 0.42-0.61; vs. 0.62, 0.52-0.71, respectively), whereas STS score performed better for in-hospital complications (0.59, 0.55-0.64). Moreover, after Cox-multivariate adjustments, only ACEF score was near to significance to predict all-cause mortality at mid-term (OR 1.7; 0.8-2.9; P = 0.058), showing the highest accuracy (0.63, 0.55-0.71). CONCLUSION: In TAVI patients, ACEF score, STS score and Logistic Euroscore provided only a moderate correlation and a low accuracy both for 30-day and medium-term outcomes. Dedicated scores are needed to properly tailor time and kind of approach.
Authors: Nicholas Chew; Jimmy Kim Fatt Hon; Wei Luen James Yip; Siew Pang Chan; Kian-Keong Poh; William Kok-Fai Kong; Kristine Leok Kheng Teoh; Tiong Cheng Yeo; Huay Cheem Tan; Edgar Lik Wui Tay Journal: Singapore Med J Date: 2016-08-12 Impact factor: 1.858
Authors: Martin Duckheim; Charlotte Bensch; Linn Kittlitz; Nin Götz; Katharina Klee; Patrick Groga-Bada; Lars Mizera; Meinrad Gawaz; Christine Zuern; Christian Eick Journal: Clin Cardiol Date: 2017-08-28 Impact factor: 2.882
Authors: Valérie M Collas; Caroline M Van De Heyning; Bernard P Paelinck; Inez E Rodrigus; Christiaan J Vrints; Johan M Bosmans Journal: Interact Cardiovasc Thorac Surg Date: 2015-12-20
Authors: Didrik Kjønås; Gry Dahle; Henrik Schirmer; Siri Malm; Jo Eidet; Lars Aaberge; Terje Steigen; Svend Aakhus; Rolf Busund; Assami Rösner Journal: Health Sci Rep Date: 2021-05-06
Authors: Tahir Hamid; Tawfiq R Choudhury; Simon G Anderson; Izhar Hashmi; Saqib Chowdhary; David Hesketh Roberts; Douglas G Fraser; Ragheb Hasan; Vaikom S Mahadevan; Richard Levy Journal: Open Heart Date: 2015-10-22
Authors: G Biondi-Zoccai; M Peruzzi; A Abbate; Z M Gertz; U Benedetto; E Tonelli; F D'Ascenzo; A Giordano; P Agostoni; G Frati Journal: Heart Lung Vessel Date: 2014
Authors: Tadhg Prendiville; Aoife Leahy; Laura Quinlan; Anastasia Saleh; Elaine Shanahan; Ahmed Gabr; Catherine Peters; Ivan Casserly; Margaret O'Connor; Rose Galvin Journal: BMJ Open Date: 2022-01-11 Impact factor: 2.692
Authors: Didrik Kjønås; Henrik Schirmer; Svend Aakhus; Jo Eidet; Siri Malm; Lars Aaberge; Rolf Busund; Assami Rösner Journal: Front Cardiovasc Med Date: 2021-12-06