| Literature DB >> 23872977 |
Guannan Sun1, Dongjun Chung, Kun Liang, Sündüz Keleş.
Abstract
Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is invaluable for identifying genome-wide binding of transcription factors and mapping of epigenomic profiles. We present a statistical protocol for analyzing ChIP-seq data. We describe guidelines for data preprocessing and quality control and provide detailed examples of identifying ChIP-enriched regions using the Bioconductor package "mosaics."Mesh:
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Year: 2013 PMID: 23872977 DOI: 10.1007/978-1-62703-514-9_12
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745