BACKGROUND: Vitamin D deficiency impairs bone health and development. OBJECTIVE: To determine the prevalence of and risk factors for vitamin D deficiency in pediatric international adoptees. METHODS: A prospective cohort (N = 189) study from a single international adoption clinic was conducted. Total 25-hydroxy vitamin D [25(OH)D] level was measured at the initial clinical assessment (within 6 months of adoption). Vitamin D deficiency was defined as a 25(OH)D <20 ng/mL (<8 nmol/L) and insufficiency as 25(OH)D <30 ng/mL (<12 nmol/L). RESULTS: Vitamin D deficiency was diagnosed in 8% and insufficiency in 27% of the cohort. Lower body mass index and longer time in an institution were associated with vitamin D deficiency and insufficiency independent of age. CONCLUSIONS: Vitamin D insufficiency was common in our cohort of international adoptees. The significance of vitamin D insufficiency on bone development during the typical "catch-up" growth following international adoption needs to be determined.
BACKGROUND:Vitamin Ddeficiency impairs bone health and development. OBJECTIVE: To determine the prevalence of and risk factors for vitamin D deficiency in pediatric international adoptees. METHODS: A prospective cohort (N = 189) study from a single international adoption clinic was conducted. Total 25-hydroxy vitamin D [25(OH)D] level was measured at the initial clinical assessment (within 6 months of adoption). Vitamin D deficiency was defined as a 25(OH)D <20 ng/mL (<8 nmol/L) and insufficiency as 25(OH)D <30 ng/mL (<12 nmol/L). RESULTS:Vitamin D deficiency was diagnosed in 8% and insufficiency in 27% of the cohort. Lower body mass index and longer time in an institution were associated with vitamin Ddeficiency and insufficiency independent of age. CONCLUSIONS:Vitamin Dinsufficiency was common in our cohort of international adoptees. The significance of vitamin Dinsufficiency on bone development during the typical "catch-up" growth following international adoption needs to be determined.
Authors: Maria G Kroupina; Liza Toemen; Musa M Aidjanov; Michael Georgieff; Mary O Hearst; John H Himes; Dana E Johnson; Bradley S Miller; Aigul M Syzdykova; Toregeldy S Sharmanov Journal: Matern Child Health J Date: 2015-06
Authors: Elena Chiappini; Francesco Vierucci; Francesca Ghetti; Maurizio de Martino; Luisa Galli Journal: PLoS One Date: 2016-09-29 Impact factor: 3.240