Literature DB >> 23870008

Retraction: Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10.

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Abstract

Entities:  

Year:  2013        PMID: 23870008      PMCID: PMC3723435          DOI: 10.1186/1472-6750-13-57

Source DB:  PubMed          Journal:  BMC Biotechnol        ISSN: 1472-6750            Impact factor:   2.563


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Retraction

The authors have retracted this article [1] due to the ethical misconduct of Karel Bezouska and misappropriation of data which fundamentally changes the main findings of the article. Specifically, the upper amino acid sequence in Figure 1 (by KB) in BMC Biotechnol 11:2 was incorrect, therefore Nit-ANigWT and Nit-ANigRec (nitrilase expressed in E. coli harbouring a nit gene from A. niger K10) were not variants of the same enzyme as hypothesized in the original article. The different biochemical properties of Nit-ANigWT and Nit-ANigRec discussed in the paper were caused by a significant difference in the primary structures of these enzymes.
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1.  Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10.

Authors:  Ondřej Kaplan; Karel Bezouška; Ondřej Plíhal; Rüdiger Ettrich; Natallia Kulik; Ondřej Vaněk; Daniel Kavan; Oldřich Benada; Anna Malandra; Ondřej Sveda; Alicja B Veselá; Anna Rinágelová; Kristýna Slámová; Maria Cantarella; Jürgen Felsberg; Jarmila Dušková; Jan Dohnálek; Michael Kotik; Vladimír Křen; Ludmila Martínková
Journal:  BMC Biotechnol       Date:  2011-01-06       Impact factor: 2.563

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