Literature DB >> 23869278

Minimally invasive surgical decompression for lumbar spinal metastases.

Jon Kimball1, Nicholas A Kusnezov, Patrick Pezeshkian, Daniel C Lu.   

Abstract

BACKGROUND: The risk of significant morbidity and mortality often outweighs the benefit of surgical resection as palliative treatment for patients with high systemic disease burden, poor cardiopulmonary status, and previous spinal surgeries. Minimally invasive surgical (MIS) approaches to decompressing metastatic epidural cord compression (MECC) can address these issues and thereby make palliation a feasible option for these patients. CASE DESCRIPTION: We present the cases of three consecutively collected patients with severe neurological compromise secondary to lumbar epidural metastases who underwent MIS decompression and achieved improved functional outcome and quality of life. The first patient is a 23-year-old female with metastatic Ewing's sarcoma who presented with 2 weeks of a right foot drop and radiculopathic pain. The next case is that of a 71-year-old male with metastatic prostate cancer who presented with significant radiculopathic L5-S1 pain and severe motor deficits in his lower extremities. The last case is that of a 73-year-old male with metastatic hepatocellular carcinoma who presented with worsening left leg weakness, paresthesia, and dysethesia. Postoperatively, each patient experienced significant improvement and almost complete enduring return of function, strength, and resolution of pain.
CONCLUSION: We demonstrate that MIS approaches to spinal decompression as palliative treatment for metastatic disease is a viable treatment in patients with a focal symptomatic lesion and comes with the benefits of decreased surgical morbidity inherent to the minimally invasive approach as well as excellent functional outcomes.

Entities:  

Keywords:  Epidural metastases; Ewing's sarcoma; metastatic; palliation; spinal decompression

Year:  2013        PMID: 23869278      PMCID: PMC3707324          DOI: 10.4103/2152-7806.113337

Source DB:  PubMed          Journal:  Surg Neurol Int        ISSN: 2152-7806


  21 in total

1.  Minimally invasive compared to open microdiscectomy for lumbar disc herniation.

Authors:  Darryl Lau; Seunggu J Han; Jasmine G Lee; Daniel C Lu; Dean Chou
Journal:  J Clin Neurosci       Date:  2010-09-20       Impact factor: 1.961

Review 2.  Diagnosis and management of metastatic spine disease. A review.

Authors:  Daniel M Sciubba; Rory J Petteys; Mark B Dekutoski; Charles G Fisher; Michael G Fehlings; Stephen L Ondra; Laurence D Rhines; Ziya L Gokaslan
Journal:  J Neurosurg Spine       Date:  2010-07

3.  Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution.

Authors:  Peter C Gerszten; Steven A Burton; Cihat Ozhasoglu; William C Welch
Journal:  Spine (Phila Pa 1976)       Date:  2007-01-15       Impact factor: 3.468

Review 4.  Minimally invasive decompression for lumbar stenosis and disc herniation.

Authors:  Sean S Armin; Langston T Holly; Larry T Khoo
Journal:  Neurosurg Focus       Date:  2008       Impact factor: 4.047

Review 5.  The surgical management of metastatic epidural compression of the spinal cord.

Authors:  N A Quraishi; Z L Gokaslan; S Boriani
Journal:  J Bone Joint Surg Br       Date:  2010-08

6.  Prediction of survival in patients with metastases in the spinal column: results based on a randomized trial of radiotherapy.

Authors:  Yvette M van der Linden; Sander P D S Dijkstra; Ernest J A Vonk; Corrie A M Marijnen; Jan Willem H Leer
Journal:  Cancer       Date:  2005-01-15       Impact factor: 6.860

Review 7.  Diagnosis and management of metastatic spine disease.

Authors:  Daniel M Sciubba; Ziya L Gokaslan
Journal:  Surg Oncol       Date:  2006-12-20       Impact factor: 3.279

Review 8.  Minimally invasive treatments for spinal metastases: vertebroplasty, kyphoplasty, and radiofrequency ablation.

Authors:  Ryan J Halpin; Bernard R Bendok; John C Liu
Journal:  J Support Oncol       Date:  2004 Jul-Aug

Review 9.  Vertebral tumors: surgical versus nonsurgical treatment.

Authors:  Edward D Simmons; Yinggang Zheng
Journal:  Clin Orthop Relat Res       Date:  2006-02       Impact factor: 4.176

10.  Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multicenter prospective observational study of 223 patients. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2007.

Authors:  Ahmed Ibrahim; Alan Crockard; Pierre Antonietti; Stefano Boriani; Cody Bünger; Alessandro Gasbarrini; Anders Grejs; Jürgen Harms; Norio Kawahara; Christian Mazel; Robert Melcher; Katsuro Tomita
Journal:  J Neurosurg Spine       Date:  2008-03
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