| Literature DB >> 23867801 |
Steven J Siegel1, John C Talpos, Mark A Geyer.
Abstract
This paper summarizes the discussions regarding animal paradigms for assessing perception at the seventh meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS). A breakout group at the meeting addressed candidate tests in animals that might best parallel the human paradigms selected previously in the CNTRICS program to assess two constructs in the domain of perception: gain control and visual integration. The perception breakout group evaluated the degree to which each of the nominated tasks met pre-specified criteria: comparability of tasks across multiple species; construct validity; neuroanatomical homology between species; and dynamic range across parametric variation.Entities:
Keywords: Event related potentials; Mismatch negative; Prepulse inhibition of startle; Visual integration
Mesh:
Year: 2013 PMID: 23867801 PMCID: PMC3849201 DOI: 10.1016/j.neubiorev.2013.06.016
Source DB: PubMed Journal: Neurosci Biobehav Rev ISSN: 0149-7634 Impact factor: 8.989