Literature DB >> 23867801

Animal models and measures of perceptual processing in schizophrenia.

Steven J Siegel1, John C Talpos, Mark A Geyer.   

Abstract

This paper summarizes the discussions regarding animal paradigms for assessing perception at the seventh meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS). A breakout group at the meeting addressed candidate tests in animals that might best parallel the human paradigms selected previously in the CNTRICS program to assess two constructs in the domain of perception: gain control and visual integration. The perception breakout group evaluated the degree to which each of the nominated tasks met pre-specified criteria: comparability of tasks across multiple species; construct validity; neuroanatomical homology between species; and dynamic range across parametric variation.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Event related potentials; Mismatch negative; Prepulse inhibition of startle; Visual integration

Mesh:

Year:  2013        PMID: 23867801      PMCID: PMC3849201          DOI: 10.1016/j.neubiorev.2013.06.016

Source DB:  PubMed          Journal:  Neurosci Biobehav Rev        ISSN: 0149-7634            Impact factor:   8.989


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