| Literature DB >> 23863995 |
Jenny Blechinger1, Hanna Pieper, Paul Marzenell, Larisa Kovbasyuk, Andrius Serva, Vytaute Starkuviene, Holger Erfle, Andriy Mokhir.
Abstract
We applied 14-mer 2'-OMe RNAs as inhibitors of selected micro RNAs. To improve their properties, we introduced a trimethoxystilbene residue at the 5'-terminus and three 2'-fluoro-2'-deoxynucleotides at the 3'-terminus to obtain potent inhibitors, whose mismatch discrimination is substantially better than that of typically applied >18-mers.Entities:
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Year: 2013 PMID： 23863995 DOI： 10.1039/c3cc43174f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222