Literature DB >> 23863201

A new role for an old player: steroid receptor RNA Activator (SRA) represses hormone inducible genes.

Miguel Beato, Guillermo P Vicent.   

Abstract

In breast cancer cells the Steroid Receptor ¬RNA Activator (SRA) acts as scaffold of a complex containing HP1γ, LSD1, HDAC1/2 and CoREST, which contributes to repression of key hormone-inducible genes that must be kept silent in the absence of hormone.

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Year:  2013        PMID： 23863201      PMCID： PMC3977916          DOI： 10.4161/trns.25777

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  38 in total

1.  Altered expression of estrogen receptor coregulators during human breast tumorigenesis.

Authors:  L C Murphy; S L Simon; A Parkes; E Leygue; H Dotzlaw; L Snell; S Troup; A Adeyinka; P H Watson
Journal:  Cancer Res       Date:  2000-11-15       Impact factor: 12.701

2.  Induction of progesterone target genes requires activation of Erk and Msk kinases and phosphorylation of histone H3.

Authors:  Guillermo P Vicent; Cecilia Ballaré; A Silvina Nacht; Jaime Clausell; Alicia Subtil-Rodríguez; Ignacio Quiles; Albert Jordan; Miguel Beato
Journal:  Mol Cell       Date:  2006-11-03       Impact factor: 17.970

3.  A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.

Authors:  Maite Huarte; Mitchell Guttman; David Feldser; Manuel Garber; Magdalena J Koziol; Daniela Kenzelmann-Broz; Ahmad M Khalil; Or Zuk; Ido Amit; Michal Rabani; Laura D Attardi; Aviv Regev; Eric S Lander; Tyler Jacks; John L Rinn
Journal:  Cell       Date:  2010-08-06       Impact factor: 41.582

4.  Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene.

Authors:  Charles E Foulds; Anna Tsimelzon; Weiwen Long; Andrew Le; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Journal:  Mol Endocrinol       Date:  2010-03-10

5.  A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA.

Authors:  M Watanabe; J Yanagisawa; H Kitagawa; K Takeyama ; S Ogawa; Y Arao; M Suzawa; Y Kobayashi; T Yano; H Yoshikawa; Y Masuhiro; S Kato
Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

6.  Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA.

Authors:  Hongjie Yao; Kevin Brick; Yvonne Evrard; Tiaojiang Xiao; R Daniel Camerini-Otero; Gary Felsenfeld
Journal:  Genes Dev       Date:  2010-10-21       Impact factor: 11.361

7.  Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor.

Authors:  Tomoshige Kino; Darrell E Hurt; Takamasa Ichijo; Nancy Nader; George P Chrousos
Journal:  Sci Signal       Date:  2010-02-02       Impact factor: 8.192

8.  Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes.

Authors:  Guillermo Pablo Vicent; A Silvina Nacht; Roser Zaurin; Jofre Font-Mateu; Daniel Soronellas; Francois Le Dily; Diana Reyes; Miguel Beato
Journal:  Genes Dev       Date:  2013-05-15       Impact factor: 11.361

9.  Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.

Authors:  Rajnish A Gupta; Nilay Shah; Kevin C Wang; Jeewon Kim; Hugo M Horlings; David J Wong; Miao-Chih Tsai; Tiffany Hung; Pedram Argani; John L Rinn; Yulei Wang; Pius Brzoska; Benjamin Kong; Rui Li; Robert B West; Marc J van de Vijver; Saraswati Sukumar; Howard Y Chang
Journal:  Nature       Date:  2010-04-15       Impact factor: 49.962

10.  Two chromatin remodeling activities cooperate during activation of hormone responsive promoters.

Authors:  Guillermo Pablo Vicent; Roser Zaurin; A Silvina Nacht; Ang Li; Jofre Font-Mateu; Francois Le Dily; Michiel Vermeulen; Matthias Mann; Miguel Beato
Journal:  PLoS Genet       Date:  2009-07-17       Impact factor: 5.917
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  8 in total

Review 1.  Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer.

Authors:  Mohammadreza Hajjari; Atefeh Khoshnevisan; Young Kee Shin
Journal:  Tumour Biol       Date:  2014-09-30

Review 2.  KDM1 class flavin-dependent protein lysine demethylases.

Authors:  Jonathan M Burg; Jennifer E Link; Brittany S Morgan; Frederick J Heller; Amanda E Hargrove; Dewey G McCafferty
Journal:  Biopolymers       Date:  2015-07       Impact factor: 2.505

3.  Idiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1.

Authors:  Leman Damla Kotan; Charlton Cooper; Şükran Darcan; Ian M Carr; Samim Özen; Yi Yan; Mohammad K Hamedani; Fatih Gürbüz; Eda Mengen; İhsan Turan; Ayça Ulubay; Gamze Akkuş; Bilgin Yüksel; A Kemal Topaloğlu; Etienne Leygue
Journal:  J Clin Res Pediatr Endocrinol       Date:  2016-04-18

Review 4.  Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication.

Authors:  Ji Wang; Chenyang Ye; Hanchu Xiong; Yong Shen; Yi Lu; Jichun Zhou; Linbo Wang
Journal:  Oncotarget       Date:  2017-01-17

Review 5.  KDM1A microenvironment, its oncogenic potential, and therapeutic significance.

Authors:  Tayaba Ismail; Hyun-Kyung Lee; Chowon Kim; Taejoon Kwon; Tae Joo Park; Hyun-Shik Lee
Journal:  Epigenetics Chromatin       Date:  2018-06-19       Impact factor: 4.954

6.  Study of lncRNA TPA in Promoting Invasion and Metastasis of Breast Cancer Mediated by TGF-β Signaling Pathway.

Authors:  Qinglin Li; Wenju Mo; Yuqin Ding; Xiaowen Ding
Journal:  Front Cell Dev Biol       Date:  2021-08-06

7.  Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and Inflammation.

Authors:  Shihab Kochumon; Hossein Arefanian; Sardar Sindhu; Steve Shenouda; Reeby Thomas; Fahd Al-Mulla; Jaakko Tuomilehto; Rasheed Ahmad
Journal:  Cells       Date:  2021-09-30       Impact factor: 6.600

Review 8.  Anti-Transcription Factor RNA Aptamers as Potential Therapeutics.

Authors:  Estefanía Mondragón; Louis James Maher
Journal:  Nucleic Acid Ther       Date:  2015-10-28       Impact factor: 5.486
  8 in total

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