Literature DB >> 23856769

KPC-producing, multidrug-resistant Klebsiella pneumoniae sequence type 258 as a typical opportunistic pathogen.

L S Tzouvelekis1, V Miriagou, S D Kotsakis, K Spyridopoulou, E Athanasiou, E Karagouni, E Tzelepi, G L Daikos.   

Abstract

The virulence of a KPC-producing Klebsiella pneumoniae sequence type 258 (ST258) strain representing those circulating in Greece was assessed in a mouse septicemia model. The strain was virtually avirulent (50% lethal dose, >10(8) and 5 × 10(7) CFU for immunocompetent and neutropenic animals, respectively). Also, it was highly susceptible to serum killing, rapidly phagocytosed in vitro, and classified as K41, which is not among the virulent capsular types. The findings indirectly support the notion that high ST258-associated mortality is largely due to inefficient antimicrobial treatment.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23856769      PMCID： PMC3811402          DOI： 10.1128/AAC.01052-13

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  Virulence and plasmid transferability of KPC Klebsiella pneumoniae at the Veterans Affairs Healthcare System of New Jersey.

Authors:  L Kristopher Siu; Jung-Chung Lin; Eric Gomez; Robert Eng; Tom Chiang
Journal:  Microb Drug Resist       Date:  2012-04-25       Impact factor: 3.431

2.  Dissociation of surface properties and "intrinsic" resistance to beta lactams in Pseudomonas aeruginosa.

Authors:  D M Livermore; T L Pitt
Journal:  J Med Microbiol       Date:  1986-11       Impact factor: 2.472

3.  Unique genes identified in the epidemic extremely drug-resistant KPC-producing Klebsiella pneumoniae sequence type 258.

Authors:  I Chmelnitsky; M Shklyar; O Hermesh; S Navon-Venezia; R Edgar; Y Carmeli
Journal:  J Antimicrob Chemother       Date:  2012-10-04       Impact factor: 5.790

4.  Measurement of phagocytosis, phagosome acidification, and intracellular killing of Staphylococcus aureus.

Authors:  Anna Sokolovska; Christine E Becker; Lynda M Stuart
Journal:  Curr Protoc Immunol       Date:  2012-11

5.  Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2.

Authors:  Michael A Bachman; Jennifer E Oyler; Samuel H Burns; Mélissa Caza; François Lépine; Charles M Dozois; Jeffrey N Weiser
Journal:  Infect Immun       Date:  2011-05-16       Impact factor: 3.441

6.  Risk factors for developing clinical infection with carbapenem-resistant Klebsiella pneumoniae in hospital patients initially only colonized with carbapenem-resistant K pneumoniae.

Authors:  Abraham Borer; Lisa Saidel-Odes; Seada Eskira; Ronit Nativ; Klaris Riesenberg; Ilana Livshiz-Riven; Francisc Schlaeffer; Michael Sherf; Nejama Peled
Journal:  Am J Infect Control       Date:  2011-09-09       Impact factor: 2.918

Review 7.  Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions.

Authors:  L S Tzouvelekis; A Markogiannakis; M Psichogiou; P T Tassios; G L Daikos
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

8.  Emergence of carbapenem-resistant Enterobacteriaceae as causes of bloodstream infections in patients with hematologic malignancies.

Authors:  Michael J Satlin; David P Calfee; Liang Chen; Kathy A Fauntleroy; Stephen J Wilson; Stephen G Jenkins; Eric J Feldman; Gail J Roboz; Tsiporah B Shore; David C Helfgott; Rosemary Soave; Barry N Kreiswirth; Thomas J Walsh
Journal:  Leuk Lymphoma       Date:  2012-09-14

Review 9.  Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors.

Authors:  R Podschun; U Ullmann
Journal:  Clin Microbiol Rev       Date:  1998-10       Impact factor: 26.132

10.  Serum resistance among Escherichia coli strains causing urinary tract infection in relation to O type and the carriage of hemolysin, colicin, and antibiotic resistance determinants.

Authors:  C Hughes; R Phillips; A P Roberts
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441
View more
  47 in total

Review 1.  Innate Immune Signaling Activated by MDR Bacteria in the Airway.

Authors:  Dane Parker; Danielle Ahn; Taylor Cohen; Alice Prince
Journal:  Physiol Rev       Date:  2016-01       Impact factor: 37.312

2.  Colistin Resistance Caused by Inactivation of the MgrB Regulator Is Not Associated with Decreased Virulence of Sequence Type 258 KPC Carbapenemase-Producing Klebsiella pneumoniae.

Authors:  Fabio Arena; Lucia Henrici De Angelis; Antonio Cannatelli; Vincenzo Di Pilato; Marina Amorese; Marco Maria D'Andrea; Tommaso Giani; Gian Maria Rossolini
Journal:  Antimicrob Agents Chemother       Date:  2016-03-25       Impact factor: 5.191

3.  Interleukin-10 Produced by Myeloid-Derived Suppressor Cells Provides Protection to Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 258 by Enhancing Its Clearance in the Airways.

Authors:  Hernán F Peñaloza; Loreani P Noguera; Danielle Ahn; Omar P Vallejos; Raquel M Castellanos; Yaneisi Vazquez; Francisco J Salazar-Echegarai; Liliana González; Isidora Suazo; Catalina Pardo-Roa; Geraldyne A Salazar; Alice Prince; Susan M Bueno
Journal:  Infect Immun       Date:  2019-04-23       Impact factor: 3.441

4.  Carbapenem-resistant Klebsiella pneumoniae exhibit variability in capsular polysaccharide and capsule associated virulence traits.

Authors:  Elizabeth Diago-Navarro; Liang Chen; Virginie Passet; Seth Burack; Amaia Ulacia-Hernando; Rosy Priya Kodiyanplakkal; Michael H Levi; Sylvain Brisse; Barry N Kreiswirth; Bettina C Fries
Journal:  J Infect Dis       Date:  2014-03-14       Impact factor: 5.226

Review 5.  The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae.

Authors:  Amy J Mathers; Gisele Peirano; Johann D D Pitout
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

6.  Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection.

Authors:  Danielle Ahn; Hernán Peñaloza; Zheng Wang; Matthew Wickersham; Dane Parker; Purvi Patel; Antonius Koller; Emily I Chen; Susan M Bueno; Anne-Catrin Uhlemann; Alice Prince
Journal:  JCI Insight       Date:  2016-10-20

Review 7.  Klebsiella pneumoniae: Going on the Offense with a Strong Defense.

Authors:  Michelle K Paczosa; Joan Mecsas
Journal:  Microbiol Mol Biol Rev       Date:  2016-06-15       Impact factor: 11.056

Review 8.  Clinical Implications of Genomic Adaptation and Evolution of Carbapenem-Resistant Klebsiella pneumoniae.

Authors:  Angela Gomez-Simmonds; Anne-Catrin Uhlemann
Journal:  J Infect Dis       Date:  2017-02-15       Impact factor: 5.226

9.  Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems.

Authors:  George L Daikos; Sophia Tsaousi; Leonidas S Tzouvelekis; Ioannis Anyfantis; Mina Psichogiou; Athina Argyropoulou; Ioanna Stefanou; Vana Sypsa; Vivi Miriagou; Martha Nepka; Sarah Georgiadou; Antonis Markogiannakis; Dimitris Goukos; Athanasios Skoutelis
Journal:  Antimicrob Agents Chemother       Date:  2014-02-10       Impact factor: 5.191

10.  CD36 Provides Host Protection Against Klebsiella pneumoniae Intrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis.

Authors:  Tolani F Olonisakin; Huihua Li; Zeyu Xiong; Elizabeth J K Kochman; Minting Yu; Yanyan Qu; Mei Hulver; Jay K Kolls; Claudette St Croix; Yohei Doi; Minh-Hong Nguyen; Robert M Q Shanks; Rama K Mallampalli; Valerian E Kagan; Anuradha Ray; Roy L Silverstein; Prabir Ray; Janet S Lee
Journal:  J Infect Dis       Date:  2016-09-28       Impact factor: 5.226
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.