Literature DB >> 23856167

HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient.

Nicola Coppola1, Giovanna Loquercio, Gilda Tonziello, Rosa Azzaro, Mariantonietta Pisaturo, Gaetano Di Costanzo, Mario Starace, Giuseppe Pasquale, Carmela Cacciapuoti, Arnolfo Petruzziello.   

Abstract

We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg.
Copyright © 2013. Published by Elsevier B.V.

Entities:  

Keywords:  ALT; HBIG; HBV; HBV infection; HBsAg; HBsAg mutants; MHR; NAT; OBI; Occult HBV infection; PC; Transfusion; alanine amino-transferase; hepatitis B immunoglobulin; hepatitis B surface antigen; hepatitis B virus; major hydrophilic region; nucleic acid amplification technique; occult HBV infection; polymerase chain reaction

Mesh：

Substances：

Year:  2013        PMID： 23856167     DOI： 10.1016/j.jcv.2013.06.020

Source DB:  PubMed          Journal:  J Clin Virol        ISSN： 1386-6532            Impact factor:   3.168


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