Literature DB >> 23855645

Negative pressure wound therapy as an adjunct in healing of chronic wounds.

Vijay Langer1, Prem S Bhandari1, Satyamoorthy Rajagopalan2, Mrinal K Mukherjee1.   

Abstract

Negative pressure wound therapy (NPWT) has emerged as a cutting-edge technology and provides an alternative solution to the problem of wounds. This study was undertaken to assess the efficacy of this technique in the treatment of chronic wounds. A prospective clinical study was used to evaluate our experience in use of NPWT in the healing of pressure ulcers and chronic wounds over 2 years. The primary end point of the study group was the time taken for appearance of healthy granulation tissue and full reepithelialisation without drainage. All patients with sepsis were excluded from the study. The statistical analysis of the data was carried out. Of the 60 patients studied, 41 had associated comorbidities including diabetes mellitus. The commonest site of occurrence was the lower limb. Coverage in the form of a flap was required at presentation in 63·33% of patients. However, after initiation of NPWT, none of them required the procedure and they healed spontaneously either by secondary intention or by skin grafting. The time taken for appearance of healthy granulation tissue was 14·36 ± 4·24 days. Complete healing of wounds occurred by 33·1 ± 10·22 days. There was a statistically significant difference in the volume of the wounds before and after the intervention (P = 0·000). Complications resulting from NPWT were minimal. This technique is an excellent adjunct to surgical debridement.
© 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  Chronic wounds; Negative pressure wound therapy; Vacuum sealing technique; Wound bed preparation; Wounds and injuries

Mesh:

Year:  2013        PMID: 23855645      PMCID: PMC7950602          DOI: 10.1111/iwj.12132

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  27 in total

1.  Vacuum-assisted wound closure for cheaper and more comfortable healing of pressure sores: a prospective study.

Authors:  Marcus B Wanner; Franz Schwarzl; Beni Strub; Guido A Zaech; Gerhard Pierer
Journal:  Scand J Plast Reconstr Surg Hand Surg       Date:  2003

Review 2.  Topical negative pressure (TNP): the evolution of a novel wound therapy.

Authors:  P E Banwell; L Téot
Journal:  J Wound Care       Date:  2003-01       Impact factor: 2.072

3.  Vacuum assisted closure therapy: a must in plastic surgery.

Authors:  Julia Claire Paul
Journal:  Plast Surg Nurs       Date:  2005 Apr-Jun

Review 4.  Wound healing: an overview.

Authors:  George Broughton; Jeffrey E Janis; Christopher E Attinger
Journal:  Plast Reconstr Surg       Date:  2006-06       Impact factor: 4.730

Review 5.  Physiology of the chronic wound.

Authors:  B C Nwomeh; D R Yager; I K Cohen
Journal:  Clin Plast Surg       Date:  1998-07       Impact factor: 2.017

Review 6.  Evidence-based recommendations for negative pressure wound therapy: treatment variables (pressure levels, wound filler and contact layer)--steps towards an international consensus.

Authors:  H Birke-Sorensen; M Malmsjo; P Rome; D Hudson; E Krug; L Berg; A Bruhin; C Caravaggi; M Chariker; M Depoorter; C Dowsett; R Dunn; F Duteille; F Ferreira; J M Francos Martínez; G Grudzien; S Ichioka; R Ingemansson; S Jeffery; C Lee; S Vig; N Runkel; R Martin; J Smith
Journal:  J Plast Reconstr Aesthet Surg       Date:  2011-08-24       Impact factor: 2.740

7.  Vacuum-assisted closure: a new method for wound control and treatment: clinical experience.

Authors:  L C Argenta; M J Morykwas
Journal:  Ann Plast Surg       Date:  1997-06       Impact factor: 1.539

8.  Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot.

Authors:  David G Armstrong; Lawrence A Lavery; Patricia Abu-Rumman; Eric H Espensen; Jefferey R Vazquez; Brent P Nixon; Andrew J M Boulton
Journal:  Ostomy Wound Manage       Date:  2002-04       Impact factor: 2.629

9.  Experience with wound VAC and delayed primary closure of contaminated soft tissue injuries in Iraq.

Authors:  Brian E Leininger; Todd E Rasmussen; David L Smith; Donald H Jenkins; Christopher Coppola
Journal:  J Trauma       Date:  2006-11

10.  A comparison of diabetic foot ulcer outcomes using negative pressure wound therapy versus historical standard of care.

Authors:  Lawrence A Lavery; Andrew J Boulton; Jeffrey A Niezgoda; Peter Sheehan
Journal:  Int Wound J       Date:  2007-06       Impact factor: 3.315

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  6 in total

1.  Combination application of ultrasonic debridement, methylene blue staining, and negative pressure wound therapy for severe pressure ulcers.

Authors:  Chao Lian; Hai-Li Liu; Yan-Ran Li; Xiao-Jun Liu; Xue-Lei Li
Journal:  Int Wound J       Date:  2019-11-03       Impact factor: 3.315

Review 2.  Chronic wounds.

Authors:  Vincent Falanga; Roslyn Rivkah Isseroff; Athena M Soulika; Marco Romanelli; David Margolis; Suzanne Kapp; Mark Granick; Keith Harding
Journal:  Nat Rev Dis Primers       Date:  2022-07-21       Impact factor: 65.038

3.  Effect of Micropower Vacuum Dressing on Promoting Wound Healing in Patients with I-II Diabetic Foot.

Authors:  Cunren Chen; Xixiong Wang; Changli Liang; Haiwei Liu
Journal:  Evid Based Complement Alternat Med       Date:  2022-05-06       Impact factor: 2.650

4.  Cyclic negative pressure wound therapy: an alternative mode to intermittent system.

Authors:  Kangwoo N Lee; Muneera Ben-Nakhi; Eun J Park; Joon P Hong
Journal:  Int Wound J       Date:  2013-12-26       Impact factor: 3.315

5.  Effect of Combining Low Temperature Plasma, Negative Pressure Wound Therapy, and Bone Marrow Mesenchymal Stem Cells on an Acute Skin Wound Healing Mouse Model.

Authors:  Hui Song Cui; So Young Joo; Yoon Soo Cho; Ji Heon Park; June-Bum Kim; Cheong Hoon Seo
Journal:  Int J Mol Sci       Date:  2020-05-23       Impact factor: 5.923

6.  Treatment of human chronic wounds with autologous extracellular matrix/stromal vascular fraction gel: A STROBE-compliant study.

Authors:  Chengliang Deng; Liangyue Wang; Jingwei Feng; Feng Lu
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.889

  6 in total

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