Literature DB >> 23852563

Incidental pineal cysts in children who undergo 3-T MRI.

Matthew T Whitehead1, Christopher C Oh, Asim F Choudhri.   

Abstract

BACKGROUND: Pineal cysts, both simple and complex, are commonly encountered in children. More cysts are being detected with MR technology; however, nearly all pineal cysts are benign and require no follow-up.
OBJECTIVE: To discover the prevalence of pineal cysts in children at our institution who have undergone high-resolution 3-T MRI.
MATERIALS AND METHODS: We retrospectively reviewed 100 consecutive 3-T brain MRIs in children ages 1 month to 17 years (mean 6.8 ± 5.1 years). We evaluated 3-D volumetric T1-W imaging, axial T2-W imaging, axial T2-W FLAIR (fluid attenuated inversion recovery) and coronal STIR (short tau inversion recovery) sequences. Pineal parenchymal and cyst volumes were measured in three planes. Cysts were analyzed for the presence and degree of complexity.
RESULTS: Pineal cysts were present in 57% of children, with a mean maximum linear dimension of 4.2 mm (range 1.5-16 mm). Of these cysts, 24.6% showed thin septations or fluid levels reflecting complexity. None of the cysts demonstrated complete T2/FLAIR signal suppression. No cyst wall thickening or nodularity was present. There was no significant difference between the ages of children with and without cysts. Cysts were more commonly encountered in girls than boys (67% vs. 52%; P = 0.043). There was a slight trend toward increasing pineal gland volume with age.
CONCLUSION: Pineal cysts are often present in children and can be incidentally detected by 3-T MRI. Characteristic-appearing pineal cysts in children are benign, incidental findings, for which follow-up is not required if there are no referable symptoms or excessive size.

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Mesh:

Year:  2013        PMID: 23852563     DOI: 10.1007/s00247-013-2742-x

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  24 in total

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2.  Serial MR imaging of pineal cysts: implications for natural history and follow-up.

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Journal:  AJR Am J Roentgenol       Date:  2001-03       Impact factor: 3.959

3.  High prevalence of pineal cysts in healthy adults demonstrated by high-resolution, noncontrast brain MR imaging.

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Journal:  AJNR Am J Neuroradiol       Date:  2007-09-20       Impact factor: 3.825

4.  Serial follow-up MRI of indeterminate cystic lesions of the pineal region: experience at a rural tertiary care referral center.

Authors:  Keith A Cauley; Grant J Linnell; Steven P Braff; Christopher G Filippi
Journal:  AJR Am J Roentgenol       Date:  2009-08       Impact factor: 3.959

5.  The pineal volume: a three-dimensional volumetric study in healthy young adults using 3.0 T MR data.

Authors:  Bo Sun; Dan Wang; Yuchun Tang; Lingzhong Fan; Xiangtao Lin; Taifei Yu; Hengtao Qi; Zhenping Li; Shuwei Liu
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Authors:  Wajd N Al-Holou; Cormac O Maher; Karin M Muraszko; Hugh J L Garton
Journal:  J Neurosurg Pediatr       Date:  2010-02       Impact factor: 2.375

8.  Prevalence of pineal cysts in children and young adults. Clinical article.

Authors:  Wajd N Al-Holou; Hugh J L Garton; Karin M Muraszko; Mohannad Ibrahim; Cormac O Maher
Journal:  J Neurosurg Pediatr       Date:  2009-09       Impact factor: 2.375

Review 9.  Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging?

Authors:  S Fakhran; E J Escott
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10.  Pineal cysts in children.

Authors:  V Lacroix-Boudhrioua; A Linglart; P Y Ancel; C Falip; P F Bougnères; C Adamsbaum
Journal:  Insights Imaging       Date:  2011-08-10
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  12 in total

Review 1.  Spectrum of intracranial incidental findings on pediatric brain magnetic resonance imaging: What clinician should know?

Authors:  Surya N Gupta; Vikash S Gupta; Andrew C White
Journal:  World J Clin Pediatr       Date:  2016-08-08

2.  Follow-up of pineal cysts in children: is it necessary?

Authors:  Miro-Pekka Jussila; Päivi Olsén; Niina Salokorpi; Maria Suo-Palosaari
Journal:  Neuroradiology       Date:  2017-09-23       Impact factor: 2.804

Review 3.  Neuroimaging in emergency: a review of possible role of pineal gland disease.

Authors:  Federico Bruno; Francesco Arrigoni; Nicola Maggialetti; Raffaele Natella; Alfonso Reginelli; Ernesto Di Cesare; Luca Brunese; Andrea Giovagnoni; Carlo Masciocchi; Alessandra Splendiani; Antonio Barile
Journal:  Gland Surg       Date:  2019-04

4.  The prevalence of pineal cyst in patients with cerebral palsy.

Authors:  Evrim Özmen; Betül Derinkuyu; Cesur Samancı; Havva Akmaz Ünlü; Tülin Hakan Demirkan; Zehra Işık Haşıloğlu; Sebuh Kuruoğlu; İbrahim Adaletli
Journal:  Diagn Interv Radiol       Date:  2015 May-Jun       Impact factor: 2.630

5.  Diffusion characteristics of pediatric pineal tumors.

Authors:  Asim F Choudhri; Matthew T Whitehead; Adeel Siddiqui; Paul Klimo; Frederick A Boop
Journal:  Neuroradiol J       Date:  2015-05-11

6.  Adolescent Development of Cortical and White Matter Structure in the NCANDA Sample: Role of Sex, Ethnicity, Puberty, and Alcohol Drinking.

Authors:  Adolf Pfefferbaum; Torsten Rohlfing; Kilian M Pohl; Barton Lane; Weiwei Chu; Dongjin Kwon; B Nolan Nichols; Sandra A Brown; Susan F Tapert; Kevin Cummins; Wesley K Thompson; Ty Brumback; M J Meloy; Terry L Jernigan; Anders Dale; Ian M Colrain; Fiona C Baker; Devin Prouty; Michael D De Bellis; James T Voyvodic; Duncan B Clark; Beatriz Luna; Tammy Chung; Bonnie J Nagel; Edith V Sullivan
Journal:  Cereb Cortex       Date:  2015-09-26       Impact factor: 5.357

7.  Physiologic pineal region, choroid plexus, and dural calcifications in the first decade of life.

Authors:  M T Whitehead; C Oh; A Raju; A F Choudhri
Journal:  AJNR Am J Neuroradiol       Date:  2014-10-29       Impact factor: 3.825

8.  Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis.

Authors:  V Dangouloff-Ros; C-J Roux; G Boulouis; R Levy; N Nicolas; C Lozach; D Grevent; F Brunelle; N Boddaert; O Naggara
Journal:  AJNR Am J Neuroradiol       Date:  2019-10-17       Impact factor: 3.825

9.  MRI-based assessment of the pineal gland in a large population of children aged 0-5 years and comparison with pineoblastoma: part II, the cystic gland.

Authors:  Selma Sirin; Marcus C de Jong; Paolo Galluzzi; Philippe Maeder; Hervé J Brisse; Jonas A Castelijns; Pim de Graaf; Sophia L Goericke
Journal:  Neuroradiology       Date:  2016-04-29       Impact factor: 2.804

10.  Prevalence and Risk Factors of Incidental Findings in Brain MRIs of Healthy Neonates-The FinnBrain Birth Cohort Study.

Authors:  Venla Kumpulainen; Satu J Lehtola; Jetro J Tuulari; Eero Silver; Anni Copeland; Riikka Korja; Hasse Karlsson; Linnea Karlsson; Harri Merisaari; Riitta Parkkola; Jani Saunavaara; Tuire Lähdesmäki; Noora M Scheinin
Journal:  Front Neurol       Date:  2020-01-08       Impact factor: 4.003

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