Literature DB >> 28942520

Follow-up of pineal cysts in children: is it necessary?

Miro-Pekka Jussila1,2, Päivi Olsén2,3, Niina Salokorpi4,5, Maria Suo-Palosaari6,7.   

Abstract

PURPOSE: Pineal cysts are common incidental findings in children undergoing magnetic resonance imaging (MRI). Several studies have suggested MRI follow-up if the cyst is larger than 10 mm. However, cysts do not usually change during follow-up. Prevalence, growth, and structure of the pineal cysts were analyzed to decide if follow-up MRI is necessary.
METHODS: A retrospective review between 2010 and 2015 was performed using 3851 MRI examinations of children aged 0-16 years to detect pineal cysts having a maximum diameter ≥ 10 mm. Eighty-one children with pineal cysts were identified and 79 of them had been controlled by MRI. Cysts were analyzed for the size, growth, and structure.
RESULTS: A total of 1.8% of the children had a pineal cyst with a diameter ≥ 10 mm. Cysts were present in 48 girls (59.3%) and 33 boys (40.7%). Most pineal cysts (70/79) did not significantly grow during the follow-up (median 10 months, range 3-145 months). A total of 11.4% (9/79) of the cysts grew with the biggest change measured from the outer cyst wall sagittal anteroposterior dimension (mean 3.4 mm ± 1.7 mm). Only one cyst grew more than 5 mm. We found no factors correlating with the cyst growth among 9 cysts that grew > 2 mm.
CONCLUSIONS: A majority of pineal cysts remained unchanged during the MRI follow-up. Results of this study suggest that routine MRI follow-up of pineal cysts is not necessary in the absence of unusual radiological characteristics or related clinical symptoms.

Entities:  

Keywords:  Brain MRI; Children; Follow-up; Incidental findings; Pineal cyst

Mesh:

Year:  2017        PMID: 28942520     DOI: 10.1007/s00234-017-1926-8

Source DB:  PubMed          Journal:  Neuroradiology        ISSN: 0028-3940            Impact factor:   2.804


  36 in total

1.  Serial MR imaging of pineal cysts: implications for natural history and follow-up.

Authors:  D P Barboriak; L Lee; J M Provenzale
Journal:  AJR Am J Roentgenol       Date:  2001-03       Impact factor: 3.959

2.  Serial follow-up MRI of indeterminate cystic lesions of the pineal region: experience at a rural tertiary care referral center.

Authors:  Keith A Cauley; Grant J Linnell; Steven P Braff; Christopher G Filippi
Journal:  AJR Am J Roentgenol       Date:  2009-08       Impact factor: 3.959

3.  Anesthesia risks associated with pediatric imaging.

Authors:  Charles Cauldwell
Journal:  Pediatr Radiol       Date:  2011-06-18

Review 4.  MRI contrast agents: basic chemistry and safety.

Authors:  Dapeng Hao; Tao Ai; Frank Goerner; Xuemei Hu; Val M Runge; Michael Tweedle
Journal:  J Magn Reson Imaging       Date:  2012-11       Impact factor: 4.813

5.  Spontaneous regression of a symptomatic pineal cyst after endoscopic third-ventriculostomy.

Authors:  A Di Chirico; F Di Rocco; F Velardi
Journal:  Childs Nerv Syst       Date:  2001-01       Impact factor: 1.475

6.  Symptomatic pineal cysts: clinical manifestations and management.

Authors:  G Michielsen; Y Benoit; E Baert; F Meire; J Caemaert
Journal:  Acta Neurochir (Wien)       Date:  2002-03       Impact factor: 2.216

7.  Prevalence of pineal cysts in children and young adults. Clinical article.

Authors:  Wajd N Al-Holou; Hugh J L Garton; Karin M Muraszko; Mohannad Ibrahim; Cormac O Maher
Journal:  J Neurosurg Pediatr       Date:  2009-09       Impact factor: 2.375

Review 8.  Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging?

Authors:  S Fakhran; E J Escott
Journal:  AJNR Am J Neuroradiol       Date:  2007-10-09       Impact factor: 3.825

9.  Incidental Pineal Cysts: Is Surveillance Necessary?

Authors:  Edward J Nevins; Kumar Das; Maneesh Bhojak; Rohan S Pinto; Mohammed N Hoque; Michael D Jenkinson; Emmanuel Chavredakis
Journal:  World Neurosurg       Date:  2016-03-02       Impact factor: 2.104

10.  MRI-based assessment of the pineal gland in a large population of children aged 0-5 years and comparison with pineoblastoma: part II, the cystic gland.

Authors:  Selma Sirin; Marcus C de Jong; Paolo Galluzzi; Philippe Maeder; Hervé J Brisse; Jonas A Castelijns; Pim de Graaf; Sophia L Goericke
Journal:  Neuroradiology       Date:  2016-04-29       Impact factor: 2.804

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  7 in total

1.  Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis.

Authors:  V Dangouloff-Ros; C-J Roux; G Boulouis; R Levy; N Nicolas; C Lozach; D Grevent; F Brunelle; N Boddaert; O Naggara
Journal:  AJNR Am J Neuroradiol       Date:  2019-10-17       Impact factor: 3.825

2.  Evaluation of pineal cysts with magnetic resonance imaging.

Authors:  Erkan Gokce; Murat Beyhan
Journal:  World J Radiol       Date:  2018-07-28

Review 3.  Dealing With Brain MRI Findings in Pediatric Patients With Endocrinological Conditions: Less Is More?

Authors:  Francesco Baldo; Maura Marin; Flora Maria Murru; Egidio Barbi; Gianluca Tornese
Journal:  Front Endocrinol (Lausanne)       Date:  2022-01-12       Impact factor: 5.555

4.  Incidental pineal gland cyst in girls with early onset of puberty.

Authors:  Gianpaolo De Filippo; Rossella Gaudino; Valeria Calcaterra; Alberto Villani; Elena Bozzola; Mauro Bozzola
Journal:  Ital J Pediatr       Date:  2022-03-21       Impact factor: 2.638

5.  Pineal cyst management: A single-institution experience spanning two decades.

Authors:  Alexander Konovalov; David Pitskhelauri; Natalia Serova; Lyudmila Shishkina; Irakliy Abramov
Journal:  Surg Neurol Int       Date:  2022-08-12

6.  Case report: Fluctuating tumor markers in a boy with gonadotropin-releasing hormone-independent precocious puberty induced by a pineal germ cell tumor.

Authors:  Alessandro Cattoni; Assunta Albanese
Journal:  Front Pediatr       Date:  2022-08-23       Impact factor: 3.569

Review 7.  Systematic review of pineal cysts surgery in pediatric patients.

Authors:  Joham Choque-Velasquez; Roberto Colasanti; Szymon Baluszek; Julio Resendiz-Nieves; Sajjad Muhammad; Christopher Ludtka; Juha Hernesniemi
Journal:  Childs Nerv Syst       Date:  2020-07-20       Impact factor: 1.475

  7 in total

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