Literature DB >> 23850542

Andirolides Q-V from the flower of andiroba (Carapa guianensis, Meliaceae).

Asami Sakamoto1, Yuji Tanaka, Takanobu Inoue, Takashi Kikuchi, Tetsuya Kajimoto, Osamu Muraoka, Takeshi Yamada, Reiko Tanaka.   

Abstract

Two new gedunins, an andirobin, two mexicanolides, and a phragmalin-type limonoid, named Andirolides Q (1), R (2), S (3), T (4), U (5), and V (6), were isolated from an oil of the flower of Carapa guianensis AUBLET (Meliaceae). Their structures have been elucidated on the basis of spectroscopic analyses using 1D and 2D NMR spectra and FABMS. Andirolide S (3) and Andirolide T (4) showed significant cytotoxic activity against the murine P388 leukemia cell line (IC₅₀ of 1.4 μM for 3; 1.8 μM for 4) and the human HL-60 leukemia cell line (IC₅₀ of 1.3 μM for 3 and 4).
© 2013.

Entities:  

Keywords:  Andirolides Q–V; Carapa guianensis; Human HL-60 leukemia cell line; Limonoid; Murine P388 leukemia cell line

Mesh：

Substances：

Year:  2013        PMID： 23850542     DOI： 10.1016/j.fitote.2013.07.001

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  7 in total

1.  Limonoids and other triterpenoids from Entandrophragma angolense.

Authors:  Isoo Youn; Zhenlong Wu; Samiya Papa; Joanna E Burdette; Bamisaye O Oyawaluja; Hyun Lee; Chun-Tao Che
Journal:  Fitoterapia       Date:  2021-02-12       Impact factor: 2.882

2.  In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production.

Authors:  Tiago B Pereira; Luiz F Rocha E Silva; Rodrigo C N Amorim; Márcia R S Melo; Rita C Zacardi de Souza; Marcos N Eberlin; Emerson S Lima; Marne C Vasconcellos; Adrian M Pohlit
Journal:  Malar J       Date:  2014-08-13       Impact factor: 2.979

3.  Hepatoprotective Limonoids from Andiroba (Carapa guianensis).

Authors:  Kiyofumi Ninomiya; Seiya Miyazawa; Kaiten Ozeki; Natsuko Matsuo; Osamu Muraoka; Takashi Kikuchi; Takeshi Yamada; Reiko Tanaka; Toshio Morikawa
Journal:  Int J Mol Sci       Date:  2016-04-19       Impact factor: 5.923

4.  Twenty-Nine New Limonoids with Skeletal Diversity from the Mangrove Plant, Xylocarpus moluccensis.

Authors:  Jianzhi Zhang; Wanshan Li; Yiguo Dai; Li Shen; Jun Wu
Journal:  Mar Drugs       Date:  2018-01-19       Impact factor: 5.118

5.  Diterpenoids and Limonoids from the Leaves and Twigs of Swietenia mahagoni.

Authors:  Wei-Ming Zhang; Jie-Qing Liu; Yuan-Yuan Deng; Jian-Jun Xia; Zhi-Run Zhang; Zhong-Rong Li; Ming-Hua Qiu
Journal:  Nat Prod Bioprospect       Date:  2014-03-11

6.  Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity.

Authors:  Arnaud F Kouam; Fei Yuan; Frédéric N Njayou; Hongtao He; Roméo F Tsayem; Babayemi O Oladejo; Fuhang Song; Paul F Moundipa; George F Gao
Journal:  Front Pharmacol       Date:  2017-09-19       Impact factor: 5.810

Review 7.  Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

Authors:  Adrian Martin Pohlit; Renata Braga Souza Lima; Gina Frausin; Luiz Francisco Rocha E Silva; Stefanie Costa Pinto Lopes; Carolina Borsoi Moraes; Pedro Cravo; Marcus Vinícius Guimarães Lacerda; André Machado Siqueira; Lucio H Freitas-Junior; Fabio Trindade Maranhão Costa
Journal:  Molecules       Date:  2013-08-02       Impact factor: 4.411
  7 in total

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