Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The papillomavirus E2 proteins.

Literature DB >> 23849793

The papillomavirus E2 proteins.

Abstract

The papillomavirus E2 proteins are pivotal to the viral life cycle and have well characterized functions in transcriptional regulation, initiation of DNA replication and partitioning the viral genome. The E2 proteins also function in vegetative DNA replication, post-transcriptional processes and possibly packaging. This review describes structural and functional aspects of the E2 proteins and their binding sites on the viral genome. It is intended to be a reference guide to this viral protein. Published by Elsevier Inc.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: E2; Genomics; HPV; Mutation; Papillomavirus; Replication; Structure; Tethering; Transcription

Mesh：

Substances：

Year: 2013 PMID： 23849793 PMCID： PMC3783563 DOI： 10.1016/j.virol.2013.06.006

Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616

261 in total

1. Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro.

Authors: A A McBride; R D Klausner; P M Howley
Journal: Proc Natl Acad Sci U S A Date: 1992-08-15 Impact factor: 11.205

2. Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator.

Authors: Noor Gammoh; Helena Sterlinko Grm; Paola Massimi; Lawrence Banks
Journal: J Virol Date: 2006-02 Impact factor: 5.103

3. Recruitment and loading of the E1 initiator protein: an ATP-dependent process catalysed by a transcription factor.

Authors: C M Sanders; A Stenlund
Journal: EMBO J Date: 1998-12-01 Impact factor: 11.598

4. Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation.

Authors: C W Lehman; M R Botchan
Journal: Proc Natl Acad Sci U S A Date: 1998-04-14 Impact factor: 11.205

5. Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9.

Authors: Sabrina Mühlen; Andreas Behren; Thomas Iftner; Christian Simon
Journal: Int J Oncol Date: 2010-08 Impact factor: 5.650

6. Transcriptional silencer of the human papillomavirus type 8 late promoter interacts alternatively with the viral trans activator E2 or with a cellular factor.

Authors: M May; K Grassmann; H Pfister; P G Fuchs
Journal: J Virol Date: 1994-06 Impact factor: 5.103

7. The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.

Authors: S H Tan; L E Leong; P A Walker; H U Bernard
Journal: J Virol Date: 1994-10 Impact factor: 5.103

8. Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter.

Authors: Daeyoup Lee; Hak-Zoo Kim; Kwi Wan Jeong; Young Sam Shim; Izumi Horikawa; J Carl Barrett; Joonho Choe
Journal: J Biol Chem Date: 2002-05-17 Impact factor: 5.157

9. Interaction of the betapapillomavirus E2 tethering protein with mitotic chromosomes.

Authors: Vandana Sekhar; Shawna C Reed; Alison A McBride
Journal: J Virol Date: 2010-01 Impact factor: 5.103

10. The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.

Authors: M H Hibma; K Raj; S J Ely; M Stanley; L Crawford
Journal: Eur J Biochem Date: 1995-04-15

155 in total

1. Human Papillomavirus 16 E2 Regulates Keratinocyte Gene Expression Relevant to Cancer and the Viral Life Cycle.

Authors: Michael R Evans; Claire D James; Molly L Bristol; Tara J Nulton; Xu Wang; Namsimar Kaur; Elizabeth A White; Brad Windle; Iain M Morgan
Journal: J Virol Date: 2019-02-05 Impact factor: 5.103

2. Heterogeneous Nuclear Ribonucleoprotein C Proteins Interact with the Human Papillomavirus Type 16 (HPV16) Early 3'-Untranslated Region and Alleviate Suppression of HPV16 Late L1 mRNA Splicing.

Authors: Soniya Dhanjal; Naoko Kajitani; Jacob Glahder; Ann-Kristin Mossberg; Cecilia Johansson; Stefan Schwartz
Journal: J Biol Chem Date: 2015-04-15 Impact factor: 5.157

The papillomavirus E2 proteins.

1. Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro.

2. Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator.

3. Recruitment and loading of the E1 initiator protein: an ATP-dependent process catalysed by a transcription factor.

4. Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation.

5. Influence of HPV16 E2 and its localisation on the expression of matrix metalloproteinase-9.

6. Transcriptional silencer of the human papillomavirus type 8 late promoter interacts alternatively with the viral trans activator E2 or with a cellular factor.

7. The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.

8. Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter.

9. Interaction of the betapapillomavirus E2 tethering protein with mitotic chromosomes.

10. The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.

1. Human Papillomavirus 16 E2 Regulates Keratinocyte Gene Expression Relevant to Cancer and the Viral Life Cycle.

2. Heterogeneous Nuclear Ribonucleoprotein C Proteins Interact with the Human Papillomavirus Type 16 (HPV16) Early 3'-Untranslated Region and Alleviate Suppression of HPV16 Late L1 mRNA Splicing.

3. Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication.

4. Papillomavirus E2 protein is regulated by specific fibroblast growth factor receptors.

Review 5. Human papillomavirus molecular biology.

6. The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA.

7. Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance.

Review 8. Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing.

Review 9. Immune therapy for human papillomaviruses-related cancers.

Review 10. Involvement of Brd4 in different steps of the papillomavirus life cycle.