Literature DB >> 23836194

Efficient capture of high-quality data on outcomes of treatment for macular diseases: the fight retinal blindness! Project.

Mark C Gillies1, Richard Walton, Julines Liong, Jennifer J Arnold, Ian McAllister, Nigel Morlet, Alex Hunyor, Robyn Guymer, Jill Keeffe, Rohan Essex, Amparo Herrera-Bond, Briony Glastonbury, Judy M Simpson, Daniel Barthelmes.   

Abstract

PURPOSE: To describe the development of a web-based high-quality data collection tool to track the outcomes of treatment of macular disease in routine practice.
METHODS: Testing of a larger data collection tool established which fields a clinician would reliably fill out. The program, which was developed using freely available software, consists of modules interacting with a core system. The module for neovascular age-related macular degeneration is described here.
RESULTS: Data for initial visits can be entered within 30 seconds, 15 seconds for follow-up visits. Fifteen centers from Australia, New Zealand, and Switzerland are currently contributing data. Finalized data from 2,052 eyes of 1,693 participants dating from January 2006 were analyzed. Median (25th and 75th percentiles) visual acuity at the index visit was 55 (41, 68) logarithm of the minimum angle of resolution letters with the following lesion types: minimally classic 17.2%, predominantly classic 24.6%, occult 52.0%, idiopathic polypoidal choroidal vasculopathy 1.2%, and retinal angiomatous proliferation 3.2%.
CONCLUSION: This software tool will facilitate the collection of large amounts of data on the routine use of treatments of neovascular age-related macular degeneration. This will allow us to analyze important potentially modifiable variables, such as the effect of different treatment patterns on visual outcomes, and to evaluate new treatments as they are introduced into practice.

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Year:  2014        PMID: 23836194     DOI: 10.1097/IAE.0b013e318296b271

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  21 in total

1.  Implementation of Lean healthcare methodology in designing an Intravitreal Injection Center: first Italian experience.

Authors:  Maria Oliva Grassi; Claudio Furino; Nicola Recchimurzo; Fabio De Vitis; Giancarlo Sborgia; Luigi Sborgia; Arianna Meleleo; Teresa Molfetta; Marina Piepoli; Paolo Locatelli; Francesco Boscia; Giovanni Alessio
Journal:  Int Ophthalmol       Date:  2020-06-08       Impact factor: 2.031

2.  A pharmacoepidemiologic study of ranibizumab and aflibercept use 2013-2016. The Fight Retinal Blindness! Project.

Authors:  Daniel Barthelmes; Vuong Nguyen; Richard Walton; Mark C Gillies; Vincent Daien
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-07-27       Impact factor: 3.117

3.  Visual Acuity Outcomes after Anti-Vascular Endothelial Growth Factor Treatment for Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report Number 19.

Authors:  Tiarnan D Keenan; Susan Vitale; Elvira Agrón; Amitha Domalpally; Andrew N Antoszyk; Michael J Elman; Traci E Clemons; Emily Y Chew
Journal:  Ophthalmol Retina       Date:  2019-06-11

Review 4.  Trends in Real-World Neovascular AMD Treatment Outcomes in the UK.

Authors:  Hemal Mehta; Leah N Kim; Thibaud Mathis; Pardis Zalmay; Faruque Ghanchi; Winfried M Amoaku; Laurent Kodjikian
Journal:  Clin Ophthalmol       Date:  2020-10-14

Review 5.  A systematic review of real-world evidence of the management of macular oedema secondary to branch retinal vein occlusion.

Authors:  Juan Lyn Ang; Sarah Ah-Moye; Leah N Kim; Vuong Nguyen; Adrian Hunt; Daniel Barthelmes; Mark C Gillies; Hemal Mehta
Journal:  Eye (Lond)       Date:  2020-04-20       Impact factor: 3.775

6.  ASSOCIATION BETWEEN ANATOMICAL AND CLINICAL OUTCOMES OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION TREATED WITH ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR.

Authors:  Vuong Nguyen; Martin Puzo; Jorge Sanchez-Monroy; Pierre-Henry Gabrielle; Catherine C Garcher; Florian Baudin; Benjamin Wolff; Laurent Castelnovo; Guillaume Michel; Louise O'Toole; Daniel Barthelmes; Mark C Gillies
Journal:  Retina       Date:  2021-07-01       Impact factor: 4.256

7.  Initial observation or treatment for diabetic macular oedema with good visual acuity: two-year outcomes comparison in routine clinical practice: data from the Fight Retinal Blindness! Registry.

Authors:  Pierre-Henry Gabrielle; Vuong Nguyen; Sanjeeb Bhandari; Hemal Mehta; Francesco Viola; Jennifer Arnold; Samantha Fraser-Bell; Daniel Barthelmes; Catherine Creuzot-Garcher; Mark Gillies
Journal:  Acta Ophthalmol       Date:  2020-11-16       Impact factor: 3.988

8.  Effects of switching from ranibizumab to aflibercept in eyes with exudative age-related macular degeneration.

Authors:  Daniel Barthelmes; Anna Campain; Phuc Nguyen; Jennifer J Arnold; Ian L McAllister; Judy M Simpson; Alex P Hunyor; Robyn Guymer; Rohan W Essex; Nigel Morlet; Mark C Gillies
Journal:  Br J Ophthalmol       Date:  2016-03-18       Impact factor: 4.638

9.  Design, development and deployment of a web-based interoperable registry for inherited retinal dystrophies in Portugal: the IRD-PT.

Authors:  João Pedro Marques; Ana Luísa Carvalho; José Henriques; Joaquim Neto Murta; Jorge Saraiva; Rufino Silva
Journal:  Orphanet J Rare Dis       Date:  2020-10-27       Impact factor: 4.123

10.  Lean approach to the management of patients undergoing intravitreal injections during COVID-19 pandemic.

Authors:  Marco Verolino; Piergiacomo Grassi; Gennaro Sosto; Gaetano D'Onofrio; Stefania De Simone; Ciro Costagliola
Journal:  Ther Adv Ophthalmol       Date:  2021-06-17
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