Literature DB >> 2382966

Counting algorithms for linkage.

N E Morton1, A Collins.   

Abstract

The Lander-Green algorithm is algebraically different from the EM algorithm that maximizes likelihood. In our experience the numerical difference is very small. Since computations are no easier or convergence faster for the Lander-Green algorithm, there is no reason to prefer it to EM. As suggested by Green (personal communication), layering is advantageous. Occasional updating of the information weights might also be considered to accelerate mapping.

Mesh:

Year:  1990        PMID: 2382966     DOI: 10.1111/j.1469-1809.1990.tb00365.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  2 in total

1.  Error filtration, interference, and the human linkage map.

Authors:  D C Shields; A Collins; K H Buetow; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

2.  New statistical methods for estimation of recombination fractions in F2 population.

Authors:  Yuan-De Tan; Xiang H F Zhang; Qianxing Mo
Journal:  BMC Bioinformatics       Date:  2017-10-03       Impact factor: 3.169

  2 in total

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