Literature DB >> 23829107

Animal models in today's translational medicine world.

Abhishek Choudhary1, Jamal A Ibdah.   

Abstract

Translational medicine drives progress of research along the continuum from basic biomedical research findings into clinical practice. Animal models play a central role in the above continuum. The recent explosion in molecular biology and generation of human physiological system in animals has led to an increasing use of in vivo animal models in today's translational medicine.

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Year:  2013        PMID： 23829107      PMCID： PMC6179858     

Source DB:  PubMed          Journal:  Mo Med        ISSN： 0026-6620


  12 in total

1.  Louis Pasteur (1822-1895).

Authors:  Guy Bordenave
Journal:  Microbes Infect       Date:  2003-05       Impact factor: 2.700

2.  REPRINT: International, multicenter randomized preclinical trials in translational stroke research: it is time to act.

Authors:  Ulrich Dirnagl; Marc Fisher
Journal:  Stroke       Date:  2012-04-24       Impact factor: 7.914

3.  Practice-based research--"Blue Highways" on the NIH roadmap.

Authors:  John M Westfall; James Mold; Lyle Fagnan
Journal:  JAMA       Date:  2007-01-24       Impact factor: 56.272

4.  Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.

Authors:  Jill L Silverman; Daniel G Smith; Stacey J Sukoff Rizzo; Michael N Karras; Sarah M Turner; Seda S Tolu; Dianne K Bryce; Deborah L Smith; Kari Fonseca; Robert H Ring; Jacqueline N Crawley
Journal:  Sci Transl Med       Date:  2012-04-25       Impact factor: 17.956

5.  mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.

Authors:  Hala Elnakat Thomas; Carol A Mercer; Larissa S Carnevalli; Jongsun Park; Jesper B Andersen; Elizabeth A Conner; Kazuhiro Tanaka; Tomoo Matsutani; Akio Iwanami; Bruce J Aronow; Liu Manway; S Michel Maira; Snorri S Thorgeirsson; Paul S Mischel; George Thomas; Sara C Kozma
Journal:  Sci Transl Med       Date:  2012-04-25       Impact factor: 17.956

6.  The meaning of translational research and why it matters.

Authors:  Steven H Woolf
Journal:  JAMA       Date:  2008-01-09       Impact factor: 56.272

7.  Resources for genetic management and genomics research on non-human primates at the National Primate Research Centers (NPRCs).

Authors:  S Kanthaswamy; J P Capitanio; C J Dubay; B Ferguson; T Folks; J C Ha; C E Hotchkiss; Z P Johnson; M G Katze; L S Kean; H Michael Kubisch; S Lank; L A Lyons; G M Miller; J Nylander; D H O'Connor; R E Palermo; D G Smith; E J Vallender; R W Wiseman; J Rogers
Journal:  J Med Primatol       Date:  2009-10       Impact factor: 0.667

8.  A knockout mouse resource for the biomedical research community.

Authors:  K C Kent Lloyd
Journal:  Ann N Y Acad Sci       Date:  2011-12       Impact factor: 5.691

9.  Defining translational research: implications for training.

Authors:  Doris McGartland Rubio; Ellie E Schoenbaum; Linda S Lee; David E Schteingart; Paul R Marantz; Karl E Anderson; Lauren Dewey Platt; Adriana Baez; Karin Esposito
Journal:  Acad Med       Date:  2010-03       Impact factor: 6.893

10.  Osteoprotection by semaphorin 3A.

Authors:  Mikihito Hayashi; Tomoki Nakashima; Masahiko Taniguchi; Tatsuhiko Kodama; Atsushi Kumanogoh; Hiroshi Takayanagi
Journal:  Nature       Date:  2012-05-03       Impact factor: 49.962
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  1 in total

1.  Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse.

Authors:  Annika Müller-Eigner; Adrián Sanz-Moreno; Irene de-Diego; Anuroop Venkateswaran Venkatasubramani; Martina Langhammer; Raffaele Gerlini; Birgit Rathkolb; Antonio Aguilar-Pimentel; Tanja Klein-Rodewald; Julia Calzada-Wack; Lore Becker; Sergio Palma-Vera; Benedikt Gille; Ignasi Forne; Axel Imhof; Chen Meng; Christina Ludwig; Franziska Koch; John T Heiker; Angela Kuhla; Vanessa Caton; Julia Brenmoehl; Henry Reyer; Jennifer Schoen; Helmut Fuchs; Valerie Gailus-Durner; Andreas Hoeflich; Martin Hrabe de Angelis; Shahaf Peleg
Journal:  Commun Biol       Date:  2022-05-03
  1 in total

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