Literature DB >> 23819641

Enhancement of the antifungal activity of antimicrobial drugs by Eugenia uniflora L.

Karla K A Santos1, Edinardo F F Matias, Saulo R Tintino, Celestina E S Souza, Maria F B M Braga, Gláucia M M Guedes, José G M Costa, Irwin R A Menezes, Henrique Douglas Melo Coutinho.   

Abstract

Candidiasis is the most frequent infection by opportunistic fungi such as Candida albicans, Candida tropicalis, and Candida krusei. Ethanol extract from Eugenia uniflora was assayed, for its antifungal activity, either alone or combined with four selected chemotherapeutic antimicrobial agents, including anphotericin B, mebendazole, nistatin, and metronidazole against these strains. The obtained results indicated that the association of the extract of E. uniflora to metronidazole showed a potential antifungal activity against C. tropicalis. However, no synergistic activity against the other strains was observed, as observed when the extract was associated with the other, not enhancing their antifungal activity.

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Year:  2013        PMID： 23819641      PMCID： PMC3719468          DOI： 10.1089/jmf.2012.0245

Source DB:  PubMed          Journal:  J Med Food        ISSN： 1096-620X            Impact factor:   2.786


  20 in total

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5.  Antimicrobial, modulatory and chemical analysis of the oil of Croton limae.

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7.  Influence of Eugenia uniflora Extract on Adhesion to Human Buccal Epithelial Cells, Biofilm Formation, and Cell Surface Hydrophobicity of Candida spp. from the Oral Cavity of Kidney Transplant Recipients.

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  7 in total

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