Literature DB >> 23813509

Tumefactive demyelination: an unusual cause of a spontaneously resolving homonymous hemianopia.

R A Dwivedi1, R E Dwivedi, J M Durnian, C A Young.   

Abstract

A 21-year-old man presented to eye casualty complaining of altered vision associated with headache and vomiting upon waking. Clinical examination was unremarkable except for a right-sided homonymous hemianopia. The MRI scan of the brain revealed a space occupying lesion within the occipital lobe and MR spectroscopy highlighted this to be inflammatory in nature, most likely a tumefactive demyelinating lesion (TDL). Lumbar puncture displayed positive oligoclonal bands. The patient was managed conservatively and made a full recovery, with normal visual fields recorded after a 3 month follow-up. This is a case of a TDL manifesting itself as an unusual cause of homonymous hemianopia; misdiagnosis of TDL is common and potentially damaging to the patient.

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Mesh:

Year:  2013        PMID: 23813509      PMCID: PMC3702905          DOI: 10.1136/bcr-2013-009363

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

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Journal:  Neurology       Date:  2002-04-23       Impact factor: 9.910

2.  Multiple sclerosis masquerading as a mass lesion.

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5.  Proton MR spectroscopy of tumefactive demyelinating lesions.

Authors:  Amit M Saindane; Soonmee Cha; Meng Law; Xiaonan Xue; Edmond A Knopp; David Zagzag
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6.  Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis.

Authors:  D J A Butteriss; A Ismail; D W Ellison; D Birchall
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7.  Distinguishing tumefactive demyelinating lesions from glioma or central nervous system lymphoma: added value of unenhanced CT compared with conventional contrast-enhanced MR imaging.

Authors:  Dae Sik Kim; Dong Gyu Na; Keon Ha Kim; Ji-Hoon Kim; Eunhee Kim; Bo La Yun; Kee-Hyun Chang
Journal:  Radiology       Date:  2009-03-04       Impact factor: 11.105

8.  Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis.

Authors:  C F Lucchinetti; R H Gavrilova; I Metz; J E Parisi; B W Scheithauer; S Weigand; K Thomsen; J Mandrekar; A Altintas; B J Erickson; F König; C Giannini; H Lassmann; L Linbo; S J Pittock; W Brück
Journal:  Brain       Date:  2008-06-05       Impact factor: 13.501

9.  Multiple Large Tumefactive MS Plaques in a Young Man: A Diagnostic Enigma and Therapeutic Challenge.

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  9 in total

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