Literature DB >> 20936974

Tumefactive demyelination-an unusual neurological presentation of HIV.

Alison Uriel1, Rachael Stow, Leann Johnson, Anoop Varma, Daniel du Plessis, Francois Gray, Amit Herwadkar, Jeremy Holland, Penny Lewthwaite, Ed Wilkins.   

Abstract

We describe 3 individuals infected with human immunodeficiency virus with unusual focal brain syndromes; magnetic resonance imaging revealed "open-ring" pattern space occupying lesions. After deterioration while the patients were receiving anti-Toxoplasma therapy, brain biopsy was performed, which revealed aggressive demyelination consistent with tumefactive demyelination. Treatment with high-dose steroids resulted in complete recovery in all cases.

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Year:  2010        PMID： 20936974     DOI： 10.1086/656812

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  7 in total

Review 1.  Atypical Pediatric Demyelinating Diseases of the Central Nervous System.

Authors:  Regina M Troxell; Alison Christy
Journal:  Curr Neurol Neurosci Rep       Date:  2019-11-26       Impact factor: 5.081

2.  Acute transient inflammatory leukoencephalopathy in HIV.

Authors:  E Tavazzi; L Magrassi; A Maccabruni; V Bargiggia; A Pichiecchio; S Delbue; P Ferrante; L Minoli; E Marchioni
Journal:  Neurol Sci       Date:  2011-01-14       Impact factor: 3.307

3.  Multiple sclerosis typical clinical and MRI findings in a patient with HIV infection.

Authors:  Alejandra González-Duarte; Carlos Ramirez; Ricardo Pinales; Juan Sierra-Madero
Journal:  J Neurovirol       Date:  2011-10-01       Impact factor: 2.643

4.  Tumefactive demyelination: an unusual cause of a spontaneously resolving homonymous hemianopia.

Authors:  R A Dwivedi; R E Dwivedi; J M Durnian; C A Young
Journal:  BMJ Case Rep       Date:  2013-06-21

5.  Clinical and imaging correlation in patients with pathologically confirmed tumefactive demyelinating lesions.

Authors:  Matthew A Tremblay; Javier E Villanueva-Meyer; Soonmee Cha; Tarik Tihan; Jeffrey M Gelfand
Journal:  J Neurol Sci       Date:  2017-08-10       Impact factor: 3.181

6.  Tumefactive demyelination in a patient with human immunodeficiency virus.

Authors:  Isaac H Solomon; Richard J Perrin; David B Clifford; Beau M Ances
Journal:  J Neurovirol       Date:  2013-05-04       Impact factor: 2.643

7.  Successful treatment of HIV-associated tumefactive demyelinating lesions with corticosteroids and cyclophosphamide: a case report.

Authors:  Serena Marita Lazzarin; Miryam Cannizzaro; Tommaso Russo; Francesca Sangalli; Marcella Callea; Bruno Colombo; Lucia Moiola; Massimo Filippi
Journal:  J Neurol       Date:  2020-11-03       Impact factor: 4.849
  7 in total

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