Literature DB >> 23811097

NLRP6 in infection and inflammation.

Paras K Anand1, Thirumala-Devi Kanneganti.   

Abstract

NLRs play fundamental roles in host-defense and inflammatory disorders. NLRP6 is a newly characterized member of this family that inhibits NF-κB and MAP-kinase dependent immune signaling to hamper anti-microbial defense. Further, NLRP6 regulates intestinal inflammation by maintaining gut microbiota composition. In this review, we examine the recent studies and emphasize the key functions regulated by NLRP6.
Copyright © 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Infection; Innate immunity; Intestinal homeostasis; Microbiota; NLR; NLRP6

Mesh：

Substances：

Year:  2013        PMID： 23811097      PMCID： PMC3810296          DOI： 10.1016/j.micinf.2013.06.009

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  64 in total

Review 1.  Intracellular NOD-like receptors in host defense and disease.

Authors:  Thirumala-Devi Kanneganti; Mohamed Lamkanfi; Gabriel Núñez
Journal:  Immunity       Date:  2007-10       Impact factor: 31.745

Review 2.  Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22.

Authors:  Gregory F Sonnenberg; Lynette A Fouser; David Artis
Journal:  Nat Immunol       Date:  2011-05       Impact factor: 25.606

3.  NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.

Authors:  Torsten B Meissner; Amy Li; Amlan Biswas; Kyoung-Hee Lee; Yuen-Joyce Liu; Erkan Bayir; Dimitrios Iliopoulos; Peter J van den Elsen; Koichi S Kobayashi
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-16       Impact factor: 11.205

4.  IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer.

Authors:  Sergei Grivennikov; Eliad Karin; Janos Terzic; Daniel Mucida; Guann-Yi Yu; Sivakumar Vallabhapurapu; Jürgen Scheller; Stefan Rose-John; Hilde Cheroutre; Lars Eckmann; Michael Karin
Journal:  Cancer Cell       Date:  2009-02-03       Impact factor: 31.743

5.  Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.

Authors:  Sophie Joly; Stephanie C Eisenbarth; Alicia K Olivier; Adam Williams; Daniel H Kaplan; Suzanne L Cassel; Richard A Flavell; Fayyaz S Sutterwala
Journal:  J Immunol       Date:  2012-10-15       Impact factor: 5.422

6.  Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis.

Authors:  Boryana K Popivanova; Kazuya Kitamura; Yu Wu; Toshikazu Kondo; Takashi Kagaya; Shiuchi Kaneko; Masanobu Oshima; Chifumi Fujii; Naofumi Mukaida
Journal:  J Clin Invest       Date:  2008-02       Impact factor: 14.808

7.  NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens.

Authors:  Paras K Anand; R K Subbarao Malireddi; John R Lukens; Peter Vogel; John Bertin; Mohamed Lamkanfi; Thirumala-Devi Kanneganti
Journal:  Nature       Date:  2012-08-16       Impact factor: 49.962

8.  Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.

Authors:  Jorge Henao-Mejia; Eran Elinav; Chengcheng Jin; Liming Hao; Wajahat Z Mehal; Till Strowig; Christoph A Thaiss; Andrew L Kau; Stephanie C Eisenbarth; Michael J Jurczak; Joao-Paulo Camporez; Gerald I Shulman; Jeffrey I Gordon; Hal M Hoffman; Richard A Flavell
Journal:  Nature       Date:  2012-02-01       Impact factor: 49.962

9.  Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest.

Authors:  Wan Seok Yang; Brent R Stockwell
Journal:  Genome Biol       Date:  2008-06-02       Impact factor: 13.583

10.  CCL5 regulation of mucosal chlamydial immunity and infection.

Authors:  Senthilkumar K Sakthivel; Udai P Singh; Shailesh Singh; Dennis D Taub; Joseph U Igietseme; James W Lillard
Journal:  BMC Microbiol       Date:  2008-08-13       Impact factor: 3.605
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  15 in total

1.  The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection.

Authors:  Amanda Costa Gonçalves; Lucas Souza Ferreira; Francine Alessandra Manente; Carolina Maria Quinello Gomes de Faria; Marisa Campos Polesi; Cleverton Roberto de Andrade; Dario Simões Zamboni; Iracilda Zeppone Carlos
Journal:  Immunology       Date:  2017-03-03       Impact factor: 7.397

2.  Effects of NLRP6 in Cerebral Ischemia/Reperfusion (I/R) Injury in Rats.

Authors:  Changchang Meng; Jinyan Zhang; Luyu Zhang; Yueting Wang; Zhenyu Li; Jing Zhao
Journal:  J Mol Neurosci       Date:  2019-07-02       Impact factor: 3.444

Review 3.  Inflammasomes in Myeloid Cells: Warriors Within.

Authors:  Sushmita Jha; W June Brickey; Jenny Pan-Yun Ting
Journal:  Microbiol Spectr       Date:  2017-01

4.  Inflammatory pathway genes associated with inter-individual variability in the trajectories of morning and evening fatigue in patients receiving chemotherapy.

Authors:  Fay Wright; Marilyn Hammer; Steven M Paul; Bradley E Aouizerat; Kord M Kober; Yvette P Conley; Bruce A Cooper; Laura B Dunn; Jon D Levine; Gail DEramo Melkus; Christine Miaskowski
Journal:  Cytokine       Date:  2017-01-19       Impact factor: 3.861

Review 5.  Inflammasomes.

Authors:  Marcel R de Zoete; Noah W Palm; Shu Zhu; Richard A Flavell
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-10-16       Impact factor: 10.005

Review 6.  Insights into inflammasome regulation: cellular, molecular, and pathogenic control of inflammasome activation.

Authors:  Naveen Challagundla; Bhaskar Saha; Reena Agrawal-Rajput
Journal:  Immunol Res       Date:  2022-05-24       Impact factor: 4.505

Review 7.  NLRP7: From inflammasome regulation to human disease.

Authors:  Jessica Carriere; Andrea Dorfleutner; Christian Stehlik
Journal:  Immunology       Date:  2021-06-30       Impact factor: 7.215

Review 8.  Debug Your Bugs - How NLRs Shape Intestinal Host-Microbe Interactions.

Authors:  Simone Lipinski; Philip Rosenstiel
Journal:  Front Immunol       Date:  2013-12-27       Impact factor: 7.561

Review 9.  Collaborative action of Toll-like and NOD-like receptors as modulators of the inflammatory response to pathogenic bacteria.

Authors:  Javier Oviedo-Boyso; Alejandro Bravo-Patiño; Víctor M Baizabal-Aguirre
Journal:  Mediators Inflamm       Date:  2014-12-01       Impact factor: 4.711

10.  Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes.

Authors:  Elke Ydens; Dieter Demon; Guillaume Lornet; Vicky De Winter; Vincent Timmerman; Mohamed Lamkanfi; Sophie Janssens
Journal:  J Neuroinflammation       Date:  2015-08-08       Impact factor: 8.322
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