INTRODUCTION: In 30% of patients with common fibular (CF) neuropathy at the fibular head, reliable localization of the site of the lesion by means of electrodiagnostic testing is challenging. METHODS: We prospectively assessed proximal CF nerve cross-sectional area (CSA) measurements and at the fibular head in 87 patients with CF neuropathy and 16 with a different condition. Reference values were obtained in 64 healthy volunteers. RESULTS: Patients with CF neuropathy had a significantly larger CF nerve CSA than controls and patient controls (P < 0.0001). Sonography localized the lesion at the fibular head in 55% and just above it in 71% of patients. Assessment of the most thickened part of the CF nerve resulted in a cut-off value of >8 mm² with a sensitivity of 90% (CI 81-95%) and a specificity of 69% (CI 58-78%). CONCLUSION: High-resolution sonography in addition to electrodiagnostic testing improves diagnostic reliability in CF neuropathy.
INTRODUCTION: In 30% of patients with common fibular (CF) neuropathy at the fibular head, reliable localization of the site of the lesion by means of electrodiagnostic testing is challenging. METHODS: We prospectively assessed proximal CF nerve cross-sectional area (CSA) measurements and at the fibular head in 87 patients with CF neuropathy and 16 with a different condition. Reference values were obtained in 64 healthy volunteers. RESULTS:Patients with CF neuropathy had a significantly larger CF nerve CSA than controls and patient controls (P < 0.0001). Sonography localized the lesion at the fibular head in 55% and just above it in 71% of patients. Assessment of the most thickened part of the CF nerve resulted in a cut-off value of >8 mm² with a sensitivity of 90% (CI 81-95%) and a specificity of 69% (CI 58-78%). CONCLUSION: High-resolution sonography in addition to electrodiagnostic testing improves diagnostic reliability in CF neuropathy.
Authors: H Stephan Goedee; Ingrid J T Herraets; Leo H Visser; Hessel Franssen; Jan-Thies H van Asseldonk; W Ludo van der Pol; Leonard H van den Berg Journal: Muscle Nerve Date: 2019-07-24 Impact factor: 3.217
Authors: H Stephan Goedee; W Ludo van der Pol; Jan-Thies H van Asseldonk; Alexander F J E Vrancken; Nicolette C Notermans; Leo H Visser; Leonard H van den Berg Journal: Neurol Clin Pract Date: 2016-08