Literature DB >> 23801258

Prion-like propagation of protein aggregation and related therapeutic strategies.

Sarah K Kaufman1, Marc I Diamond.   

Abstract

Many neurodegenerative diseases are characterized by the progressive accumulation of aggregated protein. Recent evidence suggests the prion-like propagation of protein misfolding underlies the spread of pathology observed in these diseases. This review traces our understanding of the mechanisms that underlie this phenomenon and discusses related therapeutic strategies that derive from it.

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Year:  2013        PMID： 23801258      PMCID： PMC3701767          DOI： 10.1007/s13311-013-0196-3

Source DB:  PubMed          Journal:  Neurotherapeutics        ISSN： 1878-7479            Impact factor:   7.620


  122 in total

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Journal:  Int J Biochem Cell Biol       Date:  2008-01-20       Impact factor: 5.085

2.  Resting-state functional connectivity reflects structural connectivity in the default mode network.

Authors:  Michael D Greicius; Kaustubh Supekar; Vinod Menon; Robert F Dougherty
Journal:  Cereb Cortex       Date:  2008-04-09       Impact factor: 5.357

3.  Alzheimer's disease market: hope deferred.

Authors:  Zelicia Gerald; Waldemar Ockert
Journal:  Nat Rev Drug Discov       Date:  2013-01       Impact factor: 84.694

4.  Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies.

Authors:  J H Kordower; J M Rosenstein; T J Collier; M A Burke; E Y Chen; J M Li; L Martel; A E Levey; E J Mufson; T B Freeman; C W Olanow
Journal:  J Comp Neurol       Date:  1996-06-24       Impact factor: 3.215

5.  Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma.

Authors:  Omar M A El-Agnaf; Sultan A Salem; Katerina E Paleologou; Leanne J Cooper; Nigel J Fullwood; Mark J Gibson; Martin D Curran; Jennifer A Court; David M A Mann; Shu-ichi Ikeda; Mark R Cookson; John Hardy; David Allsop
Journal:  FASEB J       Date:  2003-08-15       Impact factor: 5.191

6.  Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1.

Authors:  Marion S Buckwalter; Bronwen S Coleman; Manuel Buttini; Robin Barbour; Dale Schenk; Dora Games; Peter Seubert; Tony Wyss-Coray
Journal:  J Neurosci       Date:  2006-11-01       Impact factor: 6.167

7.  Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

Authors:  Donna M Wilcock; Amyn Rojiani; Arnon Rosenthal; Gil Levkowitz; Sangeetha Subbarao; Jennifer Alamed; David Wilson; Nedda Wilson; Melissa J Freeman; Marcia N Gordon; Dave Morgan
Journal:  J Neurosci       Date:  2004-07-07       Impact factor: 6.167

8.  Mice devoid of PrP are resistant to scrapie.

Authors:  H Büeler; A Aguzzi; A Sailer; R A Greiner; P Autenried; M Aguet; C Weissmann
Journal:  Cell       Date:  1993-07-02       Impact factor: 41.582

9.  Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons.

Authors:  Jessica W Wu; Mathieu Herman; Li Liu; Sabrina Simoes; Christopher M Acker; Helen Figueroa; Joshua I Steinberg; Martin Margittai; Rakez Kayed; Chiara Zurzolo; Gilbert Di Paolo; Karen E Duff
Journal:  J Biol Chem       Date:  2012-11-27       Impact factor: 5.157

10.  Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.

Authors:  Karah Nazor Friberg; Gene Hung; Ed Wancewicz; Kurt Giles; Chris Black; Sue Freier; Frank Bennett; Stephen J Dearmond; Yevgeniy Freyman; Pierre Lessard; Sina Ghaemmaghami; Stanley B Prusiner
Journal:  Mol Ther Nucleic Acids       Date:  2012-02-07       Impact factor: 10.183
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  16 in total

1.  Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry.

Authors:  Jennifer L Furman; Brandon B Holmes; Marc I Diamond
Journal:  J Vis Exp       Date:  2015-12-08       Impact factor: 1.355

2.  Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.

Authors:  Laura A Volpicelli-Daley; Kelvin C Luk; Virginia M-Y Lee
Journal:  Nat Protoc       Date:  2014-08-14       Impact factor: 13.491

Review 3.  Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis.

Authors:  Matthew R Brier; Jewell B Thomas; Beau M Ances
Journal:  Brain Connect       Date:  2014-06

Review 4.  Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases.

Authors:  Heiko Braak; Kelly Del Tredici
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-11-01       Impact factor: 10.005

5.  Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation.

Authors:  Xuejing Wang; Mingming Ma; Junfang Teng; Jiewen Zhang; Shuang Zhou; Ying Zhang; Erxi Wu; Xuebing Ding
Journal:  Oncotarget       Date:  2015-05-30

Review 6.  Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets.

Authors:  Amy M Pooler; Manuela Polydoro; Susanne Wegmann; Samantha B Nicholls; Tara L Spires-Jones; Bradley T Hyman
Journal:  Alzheimers Res Ther       Date:  2013-10-23       Impact factor: 6.982

7.  Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells.

Authors:  Ji-Hong Moon; Ju-Hee Lee; Uddin Md Nazim; You-Jin Lee; Jae-Won Seol; Seong-Kug Eo; John-Hwa Lee; Sang-Youel Park
Journal:  Oncotarget       Date:  2016-05-24

8.  The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases.

Authors:  Nolwen L Rey; Daniel W Wesson; Patrik Brundin
Journal:  Neurobiol Dis       Date:  2016-12-20       Impact factor: 5.996

9.  Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

Authors:  Simon Dujardin; Séverine Bégard; Raphaëlle Caillierez; Cédrick Lachaud; Lucie Delattre; Sébastien Carrier; Anne Loyens; Marie-Christine Galas; Luc Bousset; Ronald Melki; Gwennaëlle Aurégan; Philippe Hantraye; Emmanuel Brouillet; Luc Buée; Morvane Colin
Journal:  PLoS One       Date:  2014-06-27       Impact factor: 3.240

10.  Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion.

Authors:  Alba Espargaró; Maria Antònia Busquets; Joan Estelrich; Raimon Sabate
Journal:  Front Mol Neurosci       Date:  2016-04-22       Impact factor: 5.639
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