OBJECTIVE: For a general population of children, data on the relationship between vitamin D status and adiposity are limited. The aim of this study was to assess the relationships between the serum concentration of 25-hydroxyvitamin D (25-OH-D) and body fat variables measured by dual-energy X-ray absorptiometry (DXA) in a general population of Japanese children, including underweight, normal, and overweight children. METHODS: The source population comprised 521 fifth-grade children who attended either of the two public schools in Hamamatsu, Japan. Total and regional body fat mass (FM) measured by DXA were evaluated along with the serum concentration of 25-OH-D. RESULTS: We were able to analyze the FM and 25-OH-D data of 400 of the 521 children. Among boys, significant inverse relationships were observed between serum vitamin D levels and body fat variables (total FM, r = -0.201; trunk FM, r = -0.216; appendicular FM, r = -0.187; P < 0.05 for all values). Mean values of total FM and trunk FM in the vitamin D-deficient group (25-OH-D <50 nmol/L) were larger than those in the vitamin D-sufficient group (25-OH-D ≥75 nmol/L) after adjusting for confounding factors, such as sedentary behavior (P < 0.05). No relationship was observed between vitamin D status and FM among girls. CONCLUSIONS: Vitamin D deficiency was associated with higher total and trunk adiposities in a general population of Japanese children, particularly boys.
OBJECTIVE: For a general population of children, data on the relationship between vitamin D status and adiposity are limited. The aim of this study was to assess the relationships between the serum concentration of 25-hydroxyvitamin D (25-OH-D) and body fat variables measured by dual-energy X-ray absorptiometry (DXA) in a general population of Japanese children, including underweight, normal, and overweight children. METHODS: The source population comprised 521 fifth-grade children who attended either of the two public schools in Hamamatsu, Japan. Total and regional body fat mass (FM) measured by DXA were evaluated along with the serum concentration of 25-OH-D. RESULTS: We were able to analyze the FM and 25-OH-D data of 400 of the 521 children. Among boys, significant inverse relationships were observed between serum vitamin D levels and body fat variables (total FM, r = -0.201; trunk FM, r = -0.216; appendicular FM, r = -0.187; P < 0.05 for all values). Mean values of total FM and trunk FM in the vitamin D-deficient group (25-OH-D <50 nmol/L) were larger than those in the vitamin D-sufficient group (25-OH-D ≥75 nmol/L) after adjusting for confounding factors, such as sedentary behavior (P < 0.05). No relationship was observed between vitamin D status and FM among girls. CONCLUSIONS:Vitamin D deficiency was associated with higher total and trunk adiposities in a general population of Japanese children, particularly boys.
Authors: Nina O Nielsen; Marit E Jørgensen; Henrik Friis; Mads Melbye; Bolette Soborg; Charlotte Jeppesen; Marika Lundqvist; Arieh Cohen; David M Hougaard; Peter Bjerregaard Journal: PLoS One Date: 2014-12-02 Impact factor: 3.240
Authors: Shiao Wei Quah; Hazreen Abdul Majid; Nabilla Al-Sadat; Abqariyah Yahya; Tin Tin Su; Muhammad Yazid Jalaludin Journal: PLoS One Date: 2018-07-19 Impact factor: 3.240
Authors: Henrik Friis; Nyagosya Range; John Changalucha; George Praygod; Kidola Jeremiah; Daniel Faurholt-Jepsen; Henrik Krarup; Christian Mølgaard; Åse Bengaard Andersen Journal: PLoS One Date: 2013-12-06 Impact factor: 3.240