| Literature DB >> 23796192 |
J Chen1, D L Kwong, T Cao, Q Hu, L Zhang, X Ming, J Chen1, L Fu, X Guan.
Abstract
Esophageal cancer is aggressive and has poor prognosis. Esophageal squamous cell carcinoma (ESCC) is histologically the most prevalent type of esophageal cancer and ranked as the sixth leading cause of cancer death worldwide. In recent years, cancer has been widely regarded as genetic disease, as well as epigenetic abnormalities including DNA methylation, histone deacetylation, chromatin remodeling, gene imprinting and noncoding RNA regulation. In this review, we will provide a general overview of genes, proteins and microRNAs that are involved in the development of ESCC, which aims to enhance our understanding of molecular mechanisms implicated in ESCC development and progression.Entities:
Keywords: MicroRNA; esophageal cancer; proteomics; transcriptomics
Mesh：
Substances：
Year: 2013 PMID： 23796192 DOI： 10.1111/dote.12088
Source DB: PubMed Journal: Dis Esophagus ISSN： 1120-8694 Impact factor: 3.429