| Literature DB >> 23793959 |
Haijiao Liu1, Qingyuan Tan, William R Geddie, Michael A S Jewett, Nigel Phillips, Danbing Ke, Craig A Simmons, Yu Sun.
Abstract
Specific membrane capacitance (SMC) and Young's modulus are two important parameters characterizing the biophysical properties of a cell. In this work, the SMC and Young's modulus of two cell lines, RT4 and T24, corresponding to well differentiated (low grade) and poorly differentiated (high grade) urothelial cell carcinoma (UCC), respectively, were quantified using microfluidic and AFM measurements. Quantitative differences in SMC and Young's modulus values of the high-grade and low-grade UCC cells are, for the first time, reported.Entities:
Mesh:
Year: 2014 PMID: 23793959 DOI: 10.1007/s12013-013-9702-9
Source DB: PubMed Journal: Cell Biochem Biophys ISSN: 1085-9195 Impact factor: 2.194