Richard J Ross1, Ramin Shayan, Keith L Mutimer, Mark W Ashton. 1. From the *Taylor Laboratory, Department of Anatomy and Neurosciences, University of Melbourne; †Department of Plastic and Reconstructive Surgery, Royal Melbourne Hospital and University of Melbourne, Parkville; and ‡Australian Catholic University, Victoria Pde, Fitzroy, Victoria, Australia.
Abstract
BACKGROUND: Despite the widespread use of autologous fat grafting in both reconstructive and cosmetic surgery, volume retention remains a significant problem. We aimed to critically appraise the current body of literature in fat grafting to provide a framework to guide application and comparison. METHOD: Search of scientific databases and gray literature was conducted. Articles examining nonadipogenic applications of adipose tissue and those specific to breast reconstruction were excluded. RESULTS: One hundred three articles were included. These fell under the headings of donor site, effect of infiltration solution, harvest method, effect of centrifugation, reinjection method, supplementation, the role of adipose-derived stem cells, and scaffolding. CONCLUSIONS: Despite the significant research effort in this field, there remains no consensus as to the optimum technique. This stems from the vast array of research methods and short follow-up durations. Further, extrapolation of in vitro results to clinical settings has led to many conflicting practices.
BACKGROUND: Despite the widespread use of autologous fat grafting in both reconstructive and cosmetic surgery, volume retention remains a significant problem. We aimed to critically appraise the current body of literature in fat grafting to provide a framework to guide application and comparison. METHOD: Search of scientific databases and gray literature was conducted. Articles examining nonadipogenic applications of adipose tissue and those specific to breast reconstruction were excluded. RESULTS: One hundred three articles were included. These fell under the headings of donor site, effect of infiltration solution, harvest method, effect of centrifugation, reinjection method, supplementation, the role of adipose-derived stem cells, and scaffolding. CONCLUSIONS: Despite the significant research effort in this field, there remains no consensus as to the optimum technique. This stems from the vast array of research methods and short follow-up durations. Further, extrapolation of in vitro results to clinical settings has led to many conflicting practices.
Authors: Naghmeh Naderi; Emman J Combellack; Michelle Griffin; Tina Sedaghati; Muhammad Javed; Michael W Findlay; Christopher G Wallace; Afshin Mosahebi; Peter Em Butler; Alexander M Seifalian; Iain S Whitaker Journal: Int Wound J Date: 2016-02-01 Impact factor: 3.315
Authors: Natalie N Chung; Ryan C Ransom; Charles P Blackshear; Dre M Irizarry; Derek Yen; Arash Momeni; Gordon K Lee; Dung H Nguyen; Michael T Longaker; Derrick C Wan Journal: Plast Reconstr Surg Date: 2019-04 Impact factor: 4.730
Authors: Elizabeth R Zielins; Kevin Paik; Ryan C Ransom; Elizabeth A Brett; Charles P Blackshear; Anna Luan; Graham G Walmsley; David A Atashroo; Kshemendra Senarath-Yapa; Arash Momeni; Robert Rennert; Michael Sorkin; Eun Young Seo; Charles K Chan; Geoffrey C Gurtner; Michael T Longaker; Derrick C Wan Journal: Tissue Eng Part A Date: 2016-01-27 Impact factor: 3.845