Literature DB >> 23787448

Oral propranolol therapy for management of exudative retinal detachment from diffuse choroidal hemangioma in Sturge-Weber syndrome.

Raba Thapa1, Carol L Shields.   

Abstract

PURPOSE: Diffuse choroidal hemangioma (DCH), a feature of Sturge-Weber syndrome, is most often treated with whole-eye radiotherapy at stage of complications such as retinal detachment.
METHODS: This is a case report of a 17-year-old boy with DCH and exudative retinal detachment.
RESULTS: The patient was treated with propranolol at 60 mg twice a day for 2 months followed by gradual dose taper to 10 mg twice a day per month and discontinued at 7 months. The retinal detachment slowly resolved over 1 month and the retina remained attached at 10 months follow-up. There were no medication side effects.
CONCLUSIONS: We suggest that oral propranolol be considered in the armamentarium for selected DCH.

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Year:  2013        PMID: 23787448     DOI: 10.5301/ejo.5000322

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  8 in total

1.  Focal venous hypertension as a pathophysiologic mechanism for tissue hypertrophy, port-wine stains, the Sturge-Weber syndrome, and related disorders: proof of concept with novel hypothesis for underlying etiological cause (an American Ophthalmological Society thesis).

Authors:  Cameron F Parsa
Journal:  Trans Am Ophthalmol Soc       Date:  2013-09

Review 2.  Ocular Manifestations of the Sturge-Weber Syndrome.

Authors:  Kiana Hassanpour; Ramin Nourinia; Ebrahim Gerami; Ghavam Mahmoudi; Hamed Esfandiari
Journal:  J Ophthalmic Vis Res       Date:  2021-07-29

3.  Bilateral Sturge-Weber and Phakomatosis Pigmentovascularis with Glaucoma, an Overlap Syndrome.

Authors:  Bharat Patil; Gautam Sinha; Bhagabat Nayak; Reetika Sharma; Sadhana Kumari; Tanuj Dada
Journal:  Case Rep Ophthalmol Med       Date:  2015-05-06

4.  Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease.

Authors:  Virginia Albiñana; Rosa María Jiménez Escribano; Isabel Soler; Luis Rodríguez Padial; Lucia Recio-Poveda; Karina Villar Gómez de Las Heras; Luisa María Botella
Journal:  Orphanet J Rare Dis       Date:  2017-06-29       Impact factor: 4.123

5.  Progressive retinal vessel malformation in a premature infant with Sturge-Weber syndrome: a case report and a literature review of ocular manifestations in Sturge-Weber syndrome.

Authors:  Zhengping Hu; Jian Cao; Eun Young Choi; Yun Li
Journal:  BMC Ophthalmol       Date:  2021-01-22       Impact factor: 2.209

6.  Blocking Ocular Sympathetic Activity Inhibits Choroidal Neovascularization.

Authors:  Juan Carlos Martinez-Camarillo; Christine K Spee; Gloria Paulina Trujillo-Sanchez; Anthony Rodriguez; David R Hinton; Alessandra Giarola; Victor Pikov; Arun Sridhar; Mark S Humayun; Andrew C Weitz
Journal:  Front Neurosci       Date:  2022-01-10       Impact factor: 4.677

7.  The Effectiveness of Propranolol in Managing Hemorrhagic Choroidal and Exudative Retinal Detachment following Ahmed Glaucoma Valve Implantation in Sturge-Weber Syndrome: Case Report and Literature Review.

Authors:  Raid Alhayaza; Saud A Khan; Valmore A Semidey; Ohoud Owaidhah
Journal:  Case Rep Ophthalmol       Date:  2021-10-25

8.  Incidence of Sturge-Weber syndrome and associated ocular involvement in Olmsted County, Minnesota, United States.

Authors:  Heba T Rihani; Lauren A Dalvin; David O Hodge; Jose S Pulido
Journal:  Ophthalmic Genet       Date:  2020-03-31       Impact factor: 1.803

  8 in total

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