Literature DB >> 23784469

Chemistry and pharmacology of 4-hydroxylonchocarpin: a review.

Victor Kuete1, Jaures A K Noumedem, Frederic Nana.   

Abstract

4-hydroxylonchocarpin (LCP) or 2',4-dihydroxy-3',4'-(2,2-dimethylchromene) chalcone is a chalcone of the class flavonoid, with a molecular weight of 322 g/mol mostly isolated in the family Moraceae and Leguminosae. LCP was reported to have a variety of pharmacological activities such as antibacterial, antifungal, anticancer, anti-reverse transcriptase, antitubercular, antimalarial, anti-inflammatory, ornitnine decarboxylase activity and antioxidant. The hemisynthesis of the compound has been described. The present review was undertaken to bring out together the knowledge on LCP, and can serve as the start point for future research and valorization accomplishments.

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Year:  2013        PMID: 23784469     DOI: 10.1007/s11655-013-1195-7

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  22 in total

Review 1.  A review of anti-infective and anti-inflammatory chalcones.

Authors:  Zdzisława Nowakowska
Journal:  Eur J Med Chem       Date:  2006-11-15       Impact factor: 6.514

2.  A new prenylated dihydrochalcone from the leaves of Artocarpus lowii.

Authors:  Shajarahtunnur Jamil; Hasnah Mohd Sirat; Ibrahim Jantan; Norio Aimi; Mariko Kitajima
Journal:  J Nat Med       Date:  2008-02-13       Impact factor: 2.343

3.  Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors.

Authors:  Matti Ahonen; Minna Poukkula; Andrew H Baker; Masahide Kashiwagi; Hideaki Nagase; John E Eriksson; Veli-Matti Kähäri
Journal:  Oncogene       Date:  2003-04-10       Impact factor: 9.867

4.  Perivascular cells regulate endothelial membrane type-1 matrix metalloproteinase activity.

Authors:  M A Lafleur; P A Forsyth; S J Atkinson; G Murphy; D R Edwards
Journal:  Biochem Biophys Res Commun       Date:  2001-03-30       Impact factor: 3.575

5.  Prenylated chalcones, flavone and other constituents of the twigs of Dorstenia angusticornis and Dorstenia barteri var. subtriangularis.

Authors:  Bonaventure T Ngadjui; Jean Watchueng; Felix Keumedjio; Bathélémy Ngameni; Ingrid K Simo; Berhanu M Abegaz
Journal:  Phytochemistry       Date:  2005-03       Impact factor: 4.072

6.  Antibacterial activity of some natural products against bacteria expressing a multidrug-resistant phenotype.

Authors:  V Kuete; S Alibert-Franco; K O Eyong; B Ngameni; G N Folefoc; J R Nguemeving; J G Tangmouo; G W Fotso; J Komguem; B M W Ouahouo; J-M Bolla; J Chevalier; B T Ngadjui; A E Nkengfack; J-M Pagès
Journal:  Int J Antimicrob Agents       Date:  2010-12-15       Impact factor: 5.283

7.  Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri.

Authors:  Berhanu M Abegaz; Bonaventure T Ngadjui; Etienne Dongo; Bathelemy Ngameni; Mathew N Nindi; Merhatibeb Bezabih
Journal:  Phytochemistry       Date:  2002-04       Impact factor: 4.072

8.  New prenylated chalcones from Lonchocarpus neuroscapha Benth. (Cordoa piaca).

Authors:  O Gonçalves de Lima; J F de Méllo; J S de Barros Coêlho; F D de Andrade Lyra; M Machado de Albuquerque; G B Marini-Bettólo; G Delle Monache; F Delle Monache
Journal:  Farmaco Sci       Date:  1975-05

Review 9.  Trends in utilization of the pharmacological potential of chalcones.

Authors:  Daniela Ilieva Batovska; Iva Todorova Todorova
Journal:  Curr Clin Pharmacol       Date:  2010-02

10.  Multidrug-resistant tuberculosis.

Authors:  Ellen M Zager; Ruth McNerney
Journal:  BMC Infect Dis       Date:  2008-01-25       Impact factor: 3.090

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  2 in total

Review 1.  Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery.

Authors:  Gina Porras; François Chassagne; James T Lyles; Lewis Marquez; Micah Dettweiler; Akram M Salam; Tharanga Samarakoon; Sarah Shabih; Darya Raschid Farrokhi; Cassandra L Quave
Journal:  Chem Rev       Date:  2020-11-09       Impact factor: 60.622

2.  4-Benzyloxylonchocarpin and Muracatanes A-C from Ranunculus muricatus L. and Their Biological Effects.

Authors:  Hidayat Hussain; Iftikhar Ali; Daijie Wang; Nilufar Z Mamadalieva; Wahid Hussain; René Csuk; Anne Loesche; Lucie Fischer; Dan Staerk; Syariful Anam; Mashail N AlZain; Maria Mushtaq; Zaheer Ul-Haq; Riaz Ullah; Omar M Noman; Ghulam Abbas; Ivan R Green
Journal:  Biomolecules       Date:  2020-11-17
  2 in total

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