Literature DB >> 23783139

Diagnosis of acute tonsillopharyngitis in primary care: a new approach for low-resource settings.

Zuleyha Alper1, Yesim Uncu, Halis Akalin, Ilker Ercan, Melda Sinirtas, Nazan Gonul Bilgel.   

Abstract

BACKGROUND: Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings. AIM: We aimed to assess the impact of Centor criteria with the support of practical laboratory tests.
METHODS: We prospectively included patients complaining sore throat (N = 282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture.
RESULTS: In GABHS cases (N = 32, 11·3%), two of the criteria were observed to be positive in more than half of the cases (N = 19, 59·3%), while 13 (40·7%) cases met three/four criteria. The specificity of having two criteria was found to be 65·5% and increased to 91·5% after including CRP and WBC.
CONCLUSION: Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.

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Year:  2013        PMID: 23783139     DOI: 10.1179/1973947813Y.0000000071

Source DB:  PubMed          Journal:  J Chemother        ISSN: 1120-009X            Impact factor:   1.714


  7 in total

1.  Appropriateness of diagnosis of streptococcal pharyngitis among Thai community pharmacists according to the Centor criteria.

Authors:  Woranuch Saengcharoen; Pornchanok Jaisawang; Palita Udomcharoensab; Kittika Buathong; Sanguan Lerkiatbundit
Journal:  Int J Clin Pharm       Date:  2016-08-29

2.  Alteration of thiol-disulphide homeostasis in acute tonsillopharyngitis.

Authors:  Soner Sertan Kara; Ozcan Erel; Tugba Bedir Demirdag; Burcu Ceylan Cura Yayla; Belgin Gulhan; Salim Neselioglu; Meltem Polat; Gokhan Kalkan; Anil Tapisiz; Hasan Tezer
Journal:  Redox Rep       Date:  2016-04-20       Impact factor: 4.412

Review 3.  Rapid antigen detection test for group A streptococcus in children with pharyngitis.

Authors:  Jérémie F Cohen; Nathalie Bertille; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2016-07-04

4.  Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat.

Authors:  Jérémie F Cohen; Jean-Yves Pauchard; Nils Hjelm; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2020-06-04

5.  [Diagnosing streptococcal pharyngotonsillitis in children and adolescents: the limitations of the clinical features].

Authors:  Saulo Duarte Passos
Journal:  Rev Paul Pediatr       Date:  2014-12

Review 6.  Developing a framework for evidence-based grading and assessment of predictive tools for clinical decision support.

Authors:  Mohamed Khalifa; Farah Magrabi; Blanca Gallego
Journal:  BMC Med Inform Decis Mak       Date:  2019-10-29       Impact factor: 2.796

7.  Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds.

Authors:  Brian H Willis; Dyuti Coomar; Mohammed Baragilly
Journal:  Br J Gen Pract       Date:  2020-03-26       Impact factor: 5.386

  7 in total

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