Literature DB >> 25430847

Hypertension, cardiovascular risk factors and antihypertensive medication utilisation among HIV-infected individuals in Rakai, Uganda.

Laura D Sander1, Kevin Newell, Paschal Ssebbowa, David Serwadda, Thomas C Quinn, Ronald H Gray, Maria J Wawer, George Mondo, Steven Reynolds.   

Abstract

OBJECTIVES: To assess the prevalence of hypertension, elevated blood pressure and cardiovascular risk factors among HIV-positive individuals in rural Rakai District, Uganda.
METHODS: We assessed 426 HIV-positive individuals in Rakai, Uganda from 2007 to 2010. Prevalence of hypertension and elevated blood pressure assessed by clinical measurement was compared to clinician-recorded hypertension in case report forms. Multiple logistic regression and z-tests were used to examine the association of hypertension and elevated blood pressure with age, sex, body mass index (BMI), CD4 cell count and antiretroviral treatment (ART) use. For individuals on antihypertensives, medication utilisation was reviewed.
RESULTS: The prevalence of hypertension (two elevated blood pressure readings at different time points) was 8.0% (95% CI: 5.4-10.6%), and that of elevated blood pressure (one elevated blood pressure reading) was 26.3% (95% CI: 22.1-30.5%). Age ≥50 years and higher BMI were positively associated with elevated blood pressure. ART use, time on ART and CD4 cell count were not associated with hypertension. Eighty-three percent of subjects diagnosed with hypertension were on antihypertensive medications, most commonly beta-blockers and calcium channel blockers.
CONCLUSIONS: Hypertension is common among HIV-positive individuals in rural Uganda.
© 2014 John Wiley & Sons Ltd.

Entities:  

Keywords:  HIV; Ouganda; Rakai; Uganda; VIH; hypertension prevalence; prevalencia de hipertensión; prévalence de l'hypertension; traitement; tratamiento; treatment

Mesh:

Substances:

Year:  2014        PMID: 25430847      PMCID: PMC4308448          DOI: 10.1111/tmi.12443

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


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